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Profile Details
Subject Matter Expertise
Services
Work Experience
Scientific Review Officer
CSRA Inc
2015 - Present
AAAS Science and Technology Policy Fellow
National Science Foundation
2012 - 2014
Research Associate
National Academy of Sciences
2012 - 2012
Christine Mirzayan Science and Technology Policy Graduate Fellow
National Academy of Sciences
2011 - 2011
Postdoctoral Research Scientist
University of Dundee Biological Sciences
2006 - 2010
Education
PhD (Chemistry)
Pennsylvania State University
June 1998 - August 2004
BS (Chemistry, Biology)
Lock Haven University
August 1994 - May 1998
Certifications
- Certification details not provided.
Publications
JOURNAL ARTICLE
A conformationally restricted guanosine analog reveals the catalytic relevance of three structures of an RNA enzyme.
Contribution of the closing base pair to exceptional stability in RNA tetraloops: roles for molecular mimicry and electrostatic factors.
Exploring the energy landscape of a small RNA hairpin.
Mechanistic characterization of the HDV genomic ribozyme: assessing the catalytic and structural contributions of divalent metal ions within a multichannel reaction mechanism.
Folding thermodynamics and kinetics of YNMG RNA hairpins: specific incorporation of 8-bromoguanosine leads to stabilization by enhancement of the folding rate.
Restricting the conformational heterogeneity of RNA by specific incorporation of 8-bromoguanosine.
Isolation and characterization of a family of stable RNA tetraloops with the motif YNMG that participate in tertiary interactions.