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Profile Details
Contact
★★★★★
☆☆☆☆☆
USD 25 /hr
Hire Dr. Connie Vance
United States
USD 25 /hr
Profile Summary
Subject Matter Expertise
Services
Work Experience

Laboratory Safety Officer

First Flight Venture Center

January 2011 - Present

Consultant

Endacea (United States)

May 2014 - December 2016

Senior Research Scientist

Endacea (United States)

May 2004 - May 2014

Lecturer & Course Coordinator (Medicinal Chemistry I & II)

UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill

January 2008 - May 2009

Lecturer (Medicinal Chemistry I & II)

UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill

January 2006 - May 2007

Research Scientist

DarPharma Inc

May 2002 - May 2004

Post-doctoral Research Fellow

University of Michigan

April 1997 - May 2002

Education

BS (Biology)

King College

August 1986 - May 1990

Certifications
  • Certification details not provided.
Publications
JOURNAL ARTICLE
Wilson, C.N. and Vance, C.O. and Lechner, M.G. and Matuschak, G.M. and Lechner, A.J.(2014). Adenosine A1 receptor antagonist, L-97-1, improves survival and protects the kidney in a rat model of cecal ligation and puncture induced sepsis . European Journal of Pharmacology. 740. p. 346-352.
Wilson, C.N., Vance, C.O., Doyle, T.M., Brink, D.S., Matuschak, G.M., Lechner, A.J.(2012). A novel post-exposure medical countermeasure L-97-1 improves survival and acute lung injury following intratracheal infection with Yersinia pestis . Innate Immunity. 18. (3). p. 373-389.
Grubbs, R.A., Lewis, M.M., Owens-Vance, C., Gay, E.A., Jassen, A.K., Mailman, R.B., Nichols, D.E.(2004). 8,9-Dihydroxy-1,2,3,11b-tetrahydrochromeno[4,3,2,-de]isoquinoline (dinoxyline), a high affinity and potent agonist at all dopamine receptor isoforms . Bioorganic and Medicinal Chemistry. 12. (6). p. 1403-1412.
Neal Jr., C.R., Owens, C.E., Taylor, L.P., Hoversten, M.T., Akil, H., Watson Jr., S.J.(2003). Binding and GTPγS autoradiographic analysis of preproorphanin precursor peptide products at the ORL1 and opioid receptors . Journal of Chemical Neuroanatomy. 25. (4). p. 233-247.
Owens, C.E., Owens, C.E., Akil, H., Owens, C.E., Akil, H.(2002). Determinants of ligand selectivity at the κ-receptor based on the structure of the orphanin FQ receptor . Journal of Pharmacology and Experimental Therapeutics. 300. (3). p. 992-999.
Booth, R.G. and Owens, C.E. and Brown, R.L. and Bucholtz, E.C. and Lawler, C.P. and Wyrick, S.D.(1999). Putative σ3 sites in mammalian brain have histamine H1 receptor properties: Evidence from ligand binding and distribution studies with the novel H1 radioligand [3H]-(-)-trans-1-phenyl-3-aminotetralin . Brain Research. 837. (1-2). p. 95-105.
(1998). Endogenous opioids: Overview and current issues . Drug and Alcohol Dependence. 51. (1-2). p. 127-140.
Wyrick, S.D. and Booth, R.G. and Myers, A.M. and Owens, C.E. and Bucholtz, E.C. and Hooper, P.C. and Kula, N.S. and Baldessarini, R.J. and Mailman, R.B.(1995). 1-Phenyl-3-amino-1,2,3,4-tetrahydronaphthalenes and Related Derivatives as Ligands for the Neuromodulatory σ3 Receptor: Further Structure-Activity Relationships . Journal of Medicinal Chemistry. 38. (19). p. 3857-3864.
Booth, R.G., Baldessarini, R.J., Marsh, E., Booth, R.G., Booth, R.G., Baldessarini, R.J., Marsh, E., Owens, C.E.(1994). Actions of (±)-7-hydroxy-N,N-dipropylaminotetralin (7-OH-DPAT) on dopamine synthesis in limbic and extrapyramidal regions of rat brain . Brain Research. 662. (1-2). p. 283-288.
Myers, A.M. and Charifson, P.S. and Owens, C.E. and Kula, N.S. and McPhail, A.T. and Baldessarini, R.J. and Booth, R.G. and Wyrick, S.D.(1994). Conformational Analysis, Pharmacophore Identification, and Comparative Molecular Field Analysis of Ligands for the Neuromodulatory σ3 Receptor . Journal of Medicinal Chemistry. 37. (24). p. 4109-4117.
Wyrick, S.D., Booth, R.G., Myers, A.M., Owens, C.E., Kula, N.S., Baldessarini, R.J., McPhail, A.T., Mailman, R.B.(1993). Synthesis and Pharmacological Evaluation of 1-Phenyl-3-amino-1,2,3,4-tetrahydronaphthalenes as Ligands for a Novel Receptor with σ-like Neuromodulatory Activity . Journal of Medicinal Chemistry. 36. (17). p. 2542-2551.
BOOK
Blackburn, M.R., Vance, C.O., Morschl, E., Wilson, C.N.(2009). Adenosine receptors and inflammation . Handbook of Experimental Pharmacology. 193. p. 215-269.