Profile Details

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Hire Dr. Dr Chukwuma A.

United Kingdom

USD 83 /hr

Experienced cell biologist specialising in Cellular Reprogramming (iPSCs), Differentiation, and Biobanking

Profile Summary

My background is in life science with expertise in oncology, stem cells, and translational research. During the last 15 years, I have worked within academic, clinical, and industrial sectors in large-scale, high throughput projects in both technical and administrative leadership roles. During this time, I familiarised myself with strategic business planning processes and the commercial side of biomedical research, including budgeting, costings, market research, and consultation on sales. I assisted the licensing departments with the process of technology transfers and licensing platform technologies. These include setting up stem cell manufacturing facilities with customer focus, managing personnel, and a wide range of projects in oncology, haematology, and stem cells. My role also involves direct interactions with clients including scientists, industries, clinicians, patients, and regulatory authorities.

Subject Matter Expertise

• ★ Stem Cell Research
• ★ Hematology-Oncology
• ★ Gene Therapy
• ☆ STEM
• ☆ Biology/Life Sciences
• ☆ Molecular Biology
• ☆ Genetics
• ☆ PCR
• ☆ Industrial Operations Research
• ☆ Medical Sciences
• ☆ Peer Review
• ☆ Technical & Scientific Writing

Services

• Writing
• Research
• Consulting

Writing Technical Writing

Research Market Research, Systematic Literature Review

Consulting Scientific and Technical Consulting

Work Experience

Principal Scientist

Mogrify Ltd Cambridge

July 2019 - October 2019

Head of Stem Cell Core Facility

IMBA- Institute of Molecular Biotechnology Vienna, Austria

August 2016 - January 2019

Senior Staff Scientist

Wellcome Trust Sanger Institute Cambridge

November 2013 - July 2016

Senior Scientific Manager

Wellcome Trust Sanger Institute Cambridge

November 2012 - October 2013

Senior Research Assistant/Team Leader

Wellcome Trust Sanger Institute Cambridge

November 2010 - August 2012

Post-doctoral Research Fellow

Hutchison MRC Cancer Unit/University of Cambridge, UK

January 2007 - May 2010

Education

MBA (for Healthcare Sector)

Coventry University, UK

January 2020 - Present

PhD

University of Vienna

February 2002 - June 2005

BSc/Msc

University of Vienna

October 1993 - June 2000

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

(2020). Cardelino: computational integration of somatic clonal substructure and single-cell transcriptomes . Nature methods.

(2020). Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression . Nature communications.

(2020). Loss of IL-10 signaling in macrophages limits bacterial killing driven by prostaglandin E2 . The Journal of experimental medicine.

(2019). Human blood vessel organoids as a model of diabetic vasculopathy . Nature.

(2018). Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy . Human genetics.

(2017). A reversible haploid mouse embryonic stem cell biobank resource for functional genomics . Nature.

(2017). Common genetic variation drives molecular heterogeneity in human iPSCs . Nature.

(2015). Successful Generation of Human Induced Pluripotent Stem Cell Lines from Blood Samples Held at Room Temperature for up to 48 hr . Stem cell reports.

(2014). Toxin Kid uncouples DNA replication and cell division to enforce retention of plasmid R1 in Escherichia coli cells . Proceedings of the National Academy of Sciences of the United States of America.

(2013). Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes . Cell.

(2007). Bacteriophage-encoded toxins: the lambda-holin protein causes caspase-independent non-apoptotic cell death of eukaryotic cells . Cellular microbiology.

(2006). The cytotoxic activity of the bacteriophage lambda-holin protein reduces tumour growth rates in mammary cancer cell xenograft models . The journal of gene medicine.