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Profile Details
Contact
★★★★★
☆☆☆☆☆
Hire Dr. Carrie Franzen
United States
Profile Summary
Subject Matter Expertise
Services
Work Experience

Research Professional

University of Chicago

June 2019 - Present

Research Professional

University of Chicago

January 2017 - June 2019

Postdoctoral Research Fellow

Loyola University Medical Center

July 2012 - July 2015

Postdoctoral Research Fellow

Northwestern University - Chicago

April 2011 - June 2012

Postdoctoral Research Fellow

Northwestern University - Chicago

September 2006 - April 2011

Education

PhD (Molecular Genetics)

University of Illinois at Chicago

July 1999 - August 2006

Bachelor of Arts

Augustana College

September 1996 - May 1999

Certifications
  • Certification details not provided.
Publications
JOURNAL ARTICLE
(2015). Alcohol Inhibits Osteopontin-dependent Transforming Growth Factor-β1 Expression in Human Mesenchymal Stem Cells. Journal of Biological Chemistry.
(2014). Osteopontin mediates an MZF1-TGF-β1-dependent transformation of mesenchymal stem cells into cancer-associated fibroblasts in breast cancer. Oncogene.
(2014). The untapped potential of urine shed bladder cancer exosomes: biomarkers, signaling, and therapeutics. Bladder.
(2014). Apigenin inhibits TGF-β-induced VEGF expression in human prostate carcinoma cells via a Smad2/3- and Src-dependent mechanism. Molecular Carcinogenesis.
(2014). Characterization of uptake and internalization of exosomes by bladder cancer cells. Biomed Research International.
(2013). The Constituents and Potential Targets of the Extracellular Matrix: Implications for Carcinogenesis and Cancer Treatment. Carcinogenesis and Mutagenesis.
(2012). The desmosomal armadillo protein plakoglobin regulates prostate cancer cell adhesion and motility through vitronectin-dependent Src signaling. PLoS One.
(2009). The chemopreventive bioflavonoid apigenin inhibits prostate cancer cell motility through the focal adhesion kinase/Src signaling mechanism. Cancer Prevention Research.
(2009). Matrix protein CCN1 is critical for prostate carcinoma cell proliferation and TRAIL-induced apoptosis. Molecular Cancer Research.
(2008). Inhibition of HIF-1 alpha and VEGF Expression by the Chemopreventive Bioflavonoid Apigenin is Accompanied by Akt Inhibition in Human Prostate Carcinoma PC3-M Cells. Molecular Carcinogenesis.
Urothelial Cells Undergo Epithelial to Mesenchymal Transition After Exposure to Muscle Invasive Bladder Cancer Exosomes. Oncogenesis.
Urinary Exosomes: The Potential for Biomarker Utility, Intercellular Signaling, and Therapeutics in Urologic Malignancy. Journal of Urology.
CONFERENCE ABSTRACT
The extracellular matrix protein CCN1 (CYR61) sensitizes prostate carcinoma cells to TRAIL-induced apoptosis.
Exosome-Mediated Regulation of PTEN Expression in Bladder Cancer.
UROTHELIAL CELLS UNDERGO EPITHELIAL TO MESENCHYMAL TRANSITION AFTER EXPOSURE TO MUSCLE INVASIVE BLADDER CANCER EXOSOMES.
Apigenin regulates prostate cancer matrix composition, cell attachment, and cell motility through an integrin alpha 1 dependent pathway.
Apigenin regulates prostate cancer matrix composition, cell attachment, and cell motility through an integrin alpha 1 dependent pathway.
Apigenin inhibits PC3-M cell motility through the FAK/Src signaling pathway.
Novel Method Of Exosome Quantification And Cellular Uptake Using The Amnis ImageStreamX.
PLK1 Silencing in Bladder Cancer by siRNA Delivered with Exosomes.