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Profile Details
USD 100 /hr
Hire Dr. Bryan Thacker
United States
USD 100 /hr

Biomedical Scientist and Bioengineer

Profile Summary
Subject Matter Expertise
Scientific writing Grant proposal, Journal article, Regulatory documents, Clinical trial documents, Educational content
Data science & analysis Statistical analysis, Data visualization
Academic research Internet research, Evidence-based answers, Secondary data compilation, Literature search
Work Experience


TEGA Therapeutics Inc

October 2014 - Present


Ph.D. Biomedical Sciences (Biomedical Sciences)

University of California San Diego

June 2008 - June 2014

M.S. Bioengineering (Bioengineering)

University of California San Diego

September 2006 - June 2008

B.A. Biochemistry (Biochemistry)

University of Arizona

August 1999 - May 2006

B.S. Mechanical Engineering (Mechanical Engineering)

University of Arizona

August 1999 - May 2006

  • Certification details not provided.
Bryan Thacker, Jeffrey D. Esko, Chrissa A. Dwyer, Shih-Hsin Kan, Norah Al-Azzam, Charles A. Glass, Patricia Dickson, Raymond Wang, Philip L.S.M. Gordts(2018). Impaired mitophagy causes brown adipose tissue activation and cachexia in Sanfilippo syndrome type A mice . Molecular Genetics and Metabolism. 123. (2). p. S43. Elsevier {BV}
Tong, W., Dwyer, C.A., Thacker, B.E., Glass, C.A., Brown, J.R., Hamill, K., Moremen, K.W., Sarrazin, S., Gordts, P.L.S.M., Dozier, L.E., et al.(2017). Guanidinylated Neomycin Conjugation Enhances Intranasal Enzyme Replacement in the Brain . Molecular Therapy. 25. (12). p. 2743-2752.
Thacker, B.E., Seamen, E., Lawrence, R., Parker, M.W., Xu, Y., Liu, J., Vander Kooi, C.W., Esko, J.D.(2016). Expanding the 3-O-Sulfate Proteome - Enhanced Binding of Neuropilin-1 to 3-O-Sulfated Heparan Sulfate Modulates Its Activity . ACS Chemical Biology. 11. (4). p. 971-980.
Gordts, P.L.S.M., Nock, R., Son, N.-H., Ramms, B., Lew, I., Gonzales, J.C., Thacker, B.E., Basu, D., Lee, R.G., Mullick, A.E., et al.(2016). ApoC-III inhibits clearance of triglyceride-rich lipoproteins through LDL family receptors . Journal of Clinical Investigation. 126. (8). p. 2855-2866.
Bryan E. Thacker, Ding Xu, Roger Lawrence, Jeffrey D. Esko(2014). Heparan sulfate 3-O-sulfation: A rare modification in search of a function . Matrix Biology. 35. p. 60--72. Elsevier {BV}
Bryan E. Thacker, Akihito Tomiya, Jonah B. Hulst, Kentaro P. Suzuki, Shannon N. Bremner, Randy F. Gastwirt, Marion L. Greaser, Richard L. Lieber, Samuel R. Ward(2011). Passive mechanical properties and related proteins change with botulinum neurotoxin A injection of normal skeletal muscle . Journal of Orthopaedic Research. 30. (3). p. 497--502. Wiley-Blackwell
Madeline A Lancaster, Dipika J Gopal, Joon Kim, Sahar N Saleem, Jennifer L Silhavy, Carrie M Louie, Bryan E Thacker, Yuko Williams, Maha S Zaki, Joseph G Gleeson(2011). Defective Wnt-dependent cerebellar midline fusion in a mouse model of Joubert syndrome . Nature Medicine. 17. (6). p. 726--731. Springer Nature
Gesteira, T.F., Coulson-Thomas, V.J., Taunay-Rodrigues, A., Oliveira, V., Thacker, B.E., Juliano, M.A., Pasqualini, R., Arap, W., Tersariol, I.L.S., Nader, H.B., et al.(2011). Inhibitory peptides of the sulfotransferase domain of the heparan sulfate enzyme, N-Deacetylase-N-sulfotransferase-1 . Journal of Biological Chemistry. 286. (7). p. 5338-5346.
Gilad J. Regev, Choll W. Kim, Bryan E. Thacker, Akihito Tomiya, Steven R. Garfin, Samuel R. Ward, Richard L. Lieber(2010). Regional Myosin Heavy Chain Distribution in Selected Paraspinal Muscles . Spine. 35. (13). p. 1265--1270. Ovid Technologies (Wolters Kluwer Health)
Regev, G.J., Kim, C.W., Thacker, B.E., Tomiya, A., Garfin, S.R., Ward, S.R., Lieber, R.L.(2010). Regional myosin heavy chain distribution in selected paraspinal muscles . Spine. 35. (13). p. 1265-1270.
Ward, S.R., Tomiya, A., Regev, G.J., Thacker, B.E., Benzl, R.C., Kim, C.W., Lieber, R.L.(2009). Passive mechanical properties of the lumbar multifidus muscle support its role as a stabilizer . Journal of Biomechanics. 42. (10). p. 1384-1389.