{"id":7780,"date":"2020-06-18T13:36:38","date_gmt":"2020-06-18T13:36:38","guid":{"rendered":"https:\/\/www.kolabtree.com\/blog\/?p=7780"},"modified":"2020-06-18T13:36:38","modified_gmt":"2020-06-18T13:36:38","slug":"tuberculosis-the-next-big-threat-of-the-post-pandemic-world","status":"publish","type":"post","link":"https:\/\/www.kolabtree.com\/blog\/pt\/tuberculosis-the-next-big-threat-of-the-post-pandemic-world\/","title":{"rendered":"Tuberculose: a pr\u00f3xima grande amea\u00e7a do mundo p\u00f3s-pand\u00eamico"},"content":{"rendered":"<p><em>Dra. Anuja Joshi, cientista de prote\u00ednas e <a href=\"https:\/\/www.kolabtree.com\/find-an-expert\/anuja-joshi\/?utm_source=Blog&amp;utm_medium=Post&amp;utm_campaign=TB-COVID\">consultor de pesquisa<\/a> em Kolabtree, descreve como a COVID-19 est\u00e1 afetando os pa\u00edses com uma alta carga de TB.\u00a0<\/em><\/p>\n<p><span style=\"font-weight: 400;\">A pandemia do coronav\u00edrus de 2020 come\u00e7ou excepcionalmente lentamente, mas agora infectou 5 milh\u00f5es de pessoas em todo o mundo e foi respons\u00e1vel por mais de 300 mil mortes. A epidemia do <\/span><span style=\"font-weight: 400;\">doen\u00e7a coronav\u00edrus<\/span><span style=\"font-weight: 400;\">\u00a0(COVID-19) come\u00e7ou originalmente em Wuhan, China, no final de 2019 e se espalhou cada vez mais pela Europa e pelo mundo at\u00e9 fevereiro deste ano. O que foi mais surpreendente foi a taxa alarmante em que esta infec\u00e7\u00e3o viral foi contagiosa e o aumento do n\u00famero de portadores assintom\u00e1ticos. Isto n\u00e3o s\u00f3 tornou dif\u00edcil para o pessoal de sa\u00fade identificar positivamente as pessoas infectadas, mas tamb\u00e9m para o governo tentar conter estes n\u00fameros cada vez maiores. Hoje os sistemas de sa\u00fade est\u00e3o sob enorme press\u00e3o, atrasando a assist\u00eancia m\u00e9dica regular para pessoas com diferentes doen\u00e7as, como a tuberculose (TB), tornando preocupantes as situa\u00e7\u00f5es nos lares de idosos. O mundo inteiro se uniu para elaborar estrat\u00e9gias de luta contra esta doen\u00e7a e est\u00e1 colaborando al\u00e9m das fronteiras. Enquanto n\u00f3s vamos criar novas vacinas e medicamentos para o novo coronav\u00edrus e vencer esta guerra, \u00e9 importante enfrentar os impactos desta crise nos sistemas de sa\u00fade no mundo p\u00f3s-pand\u00eamico, especialmente em pa\u00edses com alta carga de TB.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">O v\u00edrus COVID-19 (SARS-CoV-2) \u00e9 altamente parecido com o antigo coronav\u00edrus da SARS, tornando imperativo olhar mais de perto para os resultados da pandemia anterior da SARS. Estudos dos sobreviventes da SRA demonstram que a fibrose progressiva dos pulm\u00f5es foi a principal raz\u00e3o para o decl\u00ednio de sua qualidade de vida. <\/span><b>Cerca de um ter\u00e7o dos pacientes com SRA mostraram comprometimento persistente da fun\u00e7\u00e3o pulmonar, um ano ap\u00f3s a recupera\u00e7\u00e3o. <\/b><span style=\"font-weight: 400;\">A fibrose pulmonar \u00e9 um dist\u00farbio pulmonar duradouro que cicatriza permanentemente os tecidos pulmonares, reduzindo sua efici\u00eancia. Estudos extensivos sobre a SRA-CoV-2 sugerem que a fibrose pulmonar \u00e9 uma das maiores complica\u00e7\u00f5es da doen\u00e7a COVID-19. Embora ainda n\u00e3o haja consenso sobre o mecanismo exato da progress\u00e3o da doen\u00e7a COVID-19, os dados existentes apontam para a possibilidade de danos pulmonares sofridos. Assim, <\/span><b>Espera-se que os sobreviventes da COVID-19 sejam suscet\u00edveis a v\u00e1rias doen\u00e7as infecciosas pulmonares como a tuberculose.<\/b><span style=\"font-weight: 400;\">uma possibilidade que at\u00e9 agora n\u00e3o foi esclarecida.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Cerca de 10 milh\u00f5es de pessoas no mundo s\u00e3o afetadas pela tuberculose com 1,5 milh\u00f5es de mortes a cada ano. Quase 90% desses casos s\u00e3o da \u00cdndia, China e outros pa\u00edses do sudeste asi\u00e1tico e da \u00c1frica do Sul que, segundo a OMS, t\u00eam um alto \u00edndice de tuberculose. Estudos recentes de modelagem baseados nesses pa\u00edses indicam que a COVID-19 induziu o bloqueio de 3 meses e um per\u00edodo de restaura\u00e7\u00e3o prolongado de 10 meses (tempo de recupera\u00e7\u00e3o necess\u00e1rio para voltar \u00e0 normalidade) poderia potencialmente levar a <\/span><b>6,3 milh\u00f5es de casos adicionais de TB entre 2020 e 2025<\/b><span style=\"font-weight: 400;\">. Uma an\u00e1lise detalhada tamb\u00e9m mostra que haveria <\/span><b>mais 1,4 milh\u00f5es de mortes por TB <\/b><span style=\"font-weight: 400;\">durante este tempo, implicando um retrocesso de 5 anos no programa de estrat\u00e9gia da TB no final.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Para a elimina\u00e7\u00e3o efetiva do poss\u00edvel aumento dos casos de TB, seria, portanto, crucial que esses pa\u00edses estivessem cientes da pr\u00f3xima amea\u00e7a e bem preparados para o diagn\u00f3stico precoce, tratamento e preven\u00e7\u00e3o das mortes por TB. Os governos, os cidad\u00e3os e as comunidades da m\u00eddia social deveriam desempenhar um papel importante na elimina\u00e7\u00e3o do estigma associado em torno da TB. A cria\u00e7\u00e3o de sistemas de vigil\u00e2ncia e monitoramento da TB, a disponibilidade de pessoal especializado em TB, e a prioriza\u00e7\u00e3o do tratamento de pacientes com TB seria a necessidade do momento. <\/span><b>O diagn\u00f3stico precoce desempenharia um papel fundamental na preven\u00e7\u00e3o do colapso dos sistemas de sa\u00fade e das mortes em massa devido \u00e0 tuberculose<\/b><span style=\"font-weight: 400;\">. Como dizem,' Stitch in time saves nine!\", estar bem preparado contribuiria muito para evitar mais uma batalha com esta doen\u00e7a mortal.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\"><strong>Refer\u00eancias<\/strong>:\u00a0<\/span><\/p>\n<ul>\n<li><span style=\"font-weight: 400;\">Heng Li, Shang-Ming Liu, Xiao-Hua Yu, Shi-Lin Tang, Chao-Ke Tang. 2019. Doen\u00e7a de Coronavirus 2019 (COVID-19): situa\u00e7\u00e3o atual e perspectivas futuras. <\/span><i><span style=\"font-weight: 400;\">Int J Agentes Antimicrob<\/span><\/i><span style=\"font-weight: 400;\">. 2020 Mar 29: 105951.\u00a0<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Wang J, Wang BJ, Yang JC, Wang MY, Chen C, Luo GX, He WF. 2019. Advances in the <a href=\"https:\/\/www.kolabtree.com\/blog\/pt\/ensuring-reproducibility-in-ai-driven-research-how-freelance-experts-can-help-in-biotech-and-healthcare\/\">pesquisa<\/a> of mechanism of pulmonary fibrosis induced by Corona Virus Disease 2019 and the corresponding therapeutic measures. Zhonghua Shao Shang Za Zhi. 2020 Mar 16;36(0): E006.\u00a0<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Relat\u00f3rio global da tuberculose de 2019. Genebra: Organiza\u00e7\u00e3o Mundial da Sa\u00fade; 2019. Licen\u00e7a: CC BY- NC-SA 3.0 IGO.\u00a0<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Ong, K. C. et al. 1 ano de fun\u00e7\u00e3o pulmonar e estado de sa\u00fade em sobreviventes de s\u00edndrome respirat\u00f3ria aguda grave. <\/span><i><span style=\"font-weight: 400;\">Peito <\/span><\/i><b>128<\/b><span style=\"font-weight: 400;\">, 1393\u20131400 (2005).\u00a0<\/span><\/li>\n<li><span style=\"font-weight: 400;\">The potential impact of the covid-19 response on tuberculosis in high-burden countries: a modelling analysis. Stop TB Partnership, Geneva; 2020. Available from: http:\/\/www.stoptb.org\/assets\/documents\/news\/Modeling%20Report_1%20May%202020_ FINAL.pdf <\/span><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>Dr. Anuja Joshi, protein scientist and research consultant on Kolabtree, outlines how COVID-19 is affecting countries with a high TB burden.\u00a0 The coronavirus pandemic of 2020 started unusually slowly but has now infected 5 million people worldwide and accounted for more than 300 thousand deaths. The outbreak of the coronavirus disease\u00a0(COVID-19) originally started in Wuhan,<\/p>\n<div class=\"read-more\"><a href=\"https:\/\/www.kolabtree.com\/blog\/pt\/tuberculosis-the-next-big-threat-of-the-post-pandemic-world\/\" title=\"Leia mais\">Leia mais<\/a><\/div>","protected":false},"author":12,"featured_media":7824,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[558],"tags":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v20.1 (Yoast SEO v20.1) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Tuberculosis: the next big threat of the post-pandemic world - The Kolabtree Blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.kolabtree.com\/blog\/pt\/tuberculosis-the-next-big-threat-of-the-post-pandemic-world\/\" \/>\n<meta property=\"og:locale\" content=\"pt_BR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Tuberculosis: the next big threat of the post-pandemic world\" \/>\n<meta property=\"og:description\" content=\"Dr. Anuja Joshi, protein scientist and research consultant on Kolabtree, outlines how COVID-19 is affecting countries with a high TB burden.\u00a0 The coronavirus pandemic of 2020 started unusually slowly but has now infected 5 million people worldwide and accounted for more than 300 thousand deaths. The outbreak of the coronavirus disease\u00a0(COVID-19) originally started in Wuhan,Read More\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.kolabtree.com\/blog\/pt\/tuberculosis-the-next-big-threat-of-the-post-pandemic-world\/\" \/>\n<meta property=\"og:site_name\" content=\"The Kolabtree Blog\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/kolabtree\" \/>\n<meta property=\"article:published_time\" content=\"2020-06-18T13:36:38+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.kolabtree.com\/blog\/wp-content\/uploads\/2020\/06\/tuberculosis.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1280\" \/>\n\t<meta property=\"og:image:height\" content=\"726\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Ramya Sriram\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@kolabtree\" \/>\n<meta name=\"twitter:site\" content=\"@kolabtree\" \/>\n<meta name=\"twitter:label1\" content=\"Escrito por\" \/>\n\t<meta name=\"twitter:data1\" content=\"Ramya Sriram\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. tempo de leitura\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutos\" \/>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Tuberculosis: the next big threat of the post-pandemic world - The Kolabtree Blog","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.kolabtree.com\/blog\/pt\/tuberculosis-the-next-big-threat-of-the-post-pandemic-world\/","og_locale":"pt_BR","og_type":"article","og_title":"Tuberculosis: the next big threat of the post-pandemic world","og_description":"Dr. Anuja Joshi, protein scientist and research consultant on Kolabtree, outlines how COVID-19 is affecting countries with a high TB burden.\u00a0 The coronavirus pandemic of 2020 started unusually slowly but has now infected 5 million people worldwide and accounted for more than 300 thousand deaths. The outbreak of the coronavirus disease\u00a0(COVID-19) originally started in Wuhan,Read More","og_url":"https:\/\/www.kolabtree.com\/blog\/pt\/tuberculosis-the-next-big-threat-of-the-post-pandemic-world\/","og_site_name":"The Kolabtree Blog","article_publisher":"https:\/\/www.facebook.com\/kolabtree","article_published_time":"2020-06-18T13:36:38+00:00","og_image":[{"width":1280,"height":726,"url":"https:\/\/www.kolabtree.com\/blog\/wp-content\/uploads\/2020\/06\/tuberculosis.jpg","type":"image\/jpeg"}],"author":"Ramya Sriram","twitter_card":"summary_large_image","twitter_creator":"@kolabtree","twitter_site":"@kolabtree","twitter_misc":{"Escrito por":"Ramya Sriram","Est. tempo de leitura":"4 minutos"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.kolabtree.com\/blog\/it\/tuberculosis-the-next-big-threat-of-the-post-pandemic-world\/#article","isPartOf":{"@id":"https:\/\/www.kolabtree.com\/blog\/it\/tuberculosis-the-next-big-threat-of-the-post-pandemic-world\/"},"author":{"name":"Ramya Sriram","@id":"https:\/\/www.kolabtree.com\/blog\/#\/schema\/person\/81992f5863a1b06d132a47822e7b4400"},"headline":"Tuberculosis: the next big threat of the post-pandemic world","datePublished":"2020-06-18T13:36:38+00:00","dateModified":"2020-06-18T13:36:38+00:00","mainEntityOfPage":{"@id":"https:\/\/www.kolabtree.com\/blog\/it\/tuberculosis-the-next-big-threat-of-the-post-pandemic-world\/"},"wordCount":734,"commentCount":0,"publisher":{"@id":"https:\/\/www.kolabtree.com\/blog\/#organization"},"articleSection":["COVID-19 resources"],"inLanguage":"pt-BR","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/www.kolabtree.com\/blog\/it\/tuberculosis-the-next-big-threat-of-the-post-pandemic-world\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/www.kolabtree.com\/blog\/it\/tuberculosis-the-next-big-threat-of-the-post-pandemic-world\/","url":"https:\/\/www.kolabtree.com\/blog\/it\/tuberculosis-the-next-big-threat-of-the-post-pandemic-world\/","name":"Tuberculosis: the next big threat of the post-pandemic world - The Kolabtree Blog","isPartOf":{"@id":"https:\/\/www.kolabtree.com\/blog\/#website"},"datePublished":"2020-06-18T13:36:38+00:00","dateModified":"2020-06-18T13:36:38+00:00","breadcrumb":{"@id":"https:\/\/www.kolabtree.com\/blog\/it\/tuberculosis-the-next-big-threat-of-the-post-pandemic-world\/#breadcrumb"},"inLanguage":"pt-BR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.kolabtree.com\/blog\/it\/tuberculosis-the-next-big-threat-of-the-post-pandemic-world\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.kolabtree.com\/blog\/it\/tuberculosis-the-next-big-threat-of-the-post-pandemic-world\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.kolabtree.com\/blog\/"},{"@type":"ListItem","position":2,"name":"Tuberculosis: the next big threat of the post-pandemic world"}]},{"@type":"WebSite","@id":"https:\/\/www.kolabtree.com\/blog\/#website","url":"https:\/\/www.kolabtree.com\/blog\/","name":"The Kolabtree Blog","description":"Expert Views on Science, Innovation and Product Development","publisher":{"@id":"https:\/\/www.kolabtree.com\/blog\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.kolabtree.com\/blog\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"pt-BR"},{"@type":"Organization","@id":"https:\/\/www.kolabtree.com\/blog\/#organization","name":"Kolabtree","url":"https:\/\/www.kolabtree.com\/blog\/","logo":{"@type":"ImageObject","inLanguage":"pt-BR","@id":"https:\/\/www.kolabtree.com\/blog\/#\/schema\/logo\/image\/","url":"","contentUrl":"","caption":"Kolabtree"},"image":{"@id":"https:\/\/www.kolabtree.com\/blog\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/kolabtree","https:\/\/twitter.com\/kolabtree","https:\/\/instagram.com\/kolabtree","https:\/\/www.linkedin.com\/company\/kolabtree","https:\/\/en.m.wikipedia.org\/wiki\/Kolabtree"]},{"@type":"Person","@id":"https:\/\/www.kolabtree.com\/blog\/#\/schema\/person\/81992f5863a1b06d132a47822e7b4400","name":"Ramya Sriram","image":{"@type":"ImageObject","inLanguage":"pt-BR","@id":"https:\/\/www.kolabtree.com\/blog\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/8100b45c960ebbbbe420e8b3f250515f?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/8100b45c960ebbbbe420e8b3f250515f?s=96&d=mm&r=g","caption":"Ramya Sriram"},"description":"Ramya Sriram manages digital content and communications at Kolabtree (kolabtree.com), the world's largest freelancing platform for scientists. 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