{"id":7763,"date":"2020-06-05T13:22:33","date_gmt":"2020-06-05T13:22:33","guid":{"rendered":"https:\/\/www.kolabtree.com\/blog\/?p=7763"},"modified":"2020-06-05T13:22:33","modified_gmt":"2020-06-05T13:22:33","slug":"role-of-anti-covid-19-antibody-testing-in-the-management-of-pandemic","status":"publish","type":"post","link":"https:\/\/www.kolabtree.com\/blog\/pt\/role-of-anti-covid-19-antibody-testing-in-the-management-of-pandemic\/","title":{"rendered":"Papel dos testes de anticorpos anti-COVID-19 na gest\u00e3o de pandemias"},"content":{"rendered":"

A doen\u00e7a coronav\u00edrus \u00e9 uma doen\u00e7a infecciosa respirat\u00f3ria preliminar causada por um novo coronav\u00edrus tamb\u00e9m chamado de COVID-19 ou SARS-CoV-2. Foi declarada como uma pandemia global pela Organiza\u00e7\u00e3o Mundial da Sa\u00fade (OMS) em 11 de mar\u00e7o de 2020, afetando mais de 210 pa\u00edses e territ\u00f3rios ao redor do mundo.<\/span><\/p>\n

Como sabemos, o v\u00edrus COVID-19 se espalhou principalmente atrav\u00e9s de got\u00edculas de saliva ou descarga do nariz quando uma pessoa infectada tosse ou espirra. O teste \u00e9 feito em amostras respirat\u00f3rias como esfrega\u00e7o nasofar\u00edngeo ou amostra de expectora\u00e7\u00e3o usando a Rea\u00e7\u00e3o em Cadeia de Polimerase de Transcri\u00e7\u00e3o Reversa (RT-PCR). Entretanto, o teste \u00e9 demorado e caro, al\u00e9m de n\u00e3o estar prontamente dispon\u00edvel para todos os centros.<\/span>\u00a0<\/span><\/p>\n

Como uma alternativa importante, o diagn\u00f3stico r\u00e1pido baseado em anticorpos est\u00e1 escolhendo o momento na gest\u00e3o da COVID-19. Assim como outras infec\u00e7\u00f5es virais, a COVID-19 tamb\u00e9m produz anticorpos que come\u00e7am a partir de 3 dias. Estes anticorpos podem ser detectados usando kits de teste r\u00e1pido (sorologia) em poucos minutos usando apenas uma gota de sangue, plasma, ou soro dos pacientes.<\/span><\/p><\/blockquote>\n

Na situa\u00e7\u00e3o atual, um teste r\u00e1pido de detec\u00e7\u00e3o de anticorpos \u00e9 \u00fatil para a triagem geral das massas, a fim de compreender a propaga\u00e7\u00e3o da infec\u00e7\u00e3o. Uma grande pesquisa usando um teste r\u00e1pido de anticorpos \u00e9 poss\u00edvel e crucial para triagem dos casos assintom\u00e1ticos ou portadores, assim como para conhecer a for\u00e7a da imunidade do rebanho na popula\u00e7\u00e3o em quest\u00e3o. <\/span><\/p>\n

Al\u00e9m disso, tamb\u00e9m \u00e9 \u00fatil para a avalia\u00e7\u00e3o do progn\u00f3stico ao confirmar o desenvolvimento da imunidade em um paciente COVID-19 positivo uma vez que o teste RT-PCR para o v\u00edrus se torna negativo. Quando tivermos vacinas espec\u00edficas dispon\u00edveis para a COVID-19, o teste de anticorpos tamb\u00e9m seria \u00fatil para identificar a efic\u00e1cia da vacina.<\/span><\/p>\n

Sem nenhum tratamento anti-viral estabelecido ou vacina dispon\u00edvel para a infec\u00e7\u00e3o pela COVID-19, a identifica\u00e7\u00e3o dos pacientes infectados, bem como de indiv\u00edduos imunes, seria necess\u00e1ria para ajudar a administrar corretamente a pandemia. Isto s\u00f3 pode ser estimado atrav\u00e9s de testes de anticorpos em massa da popula\u00e7\u00e3o para garantir que eles tenham a imunidade necess\u00e1ria para evitar a propaga\u00e7\u00e3o da doen\u00e7a quando reabrirmos nosso estilo de vida de rotina, uma esp\u00e9cie de \"passaporte de imunidade\".<\/span><\/p>\n

Cuidado com as falsas cren\u00e7as<\/i><\/strong><\/p>\n

Com as atuais evid\u00eancias, n\u00e3o \u00e9 s\u00e1bio afirmar que a presen\u00e7a de anticorpos anti-corona confere prote\u00e7\u00e3o contra a segunda infec\u00e7\u00e3o pelo v\u00edrus. Infelizmente, para atender \u00e0s altas exig\u00eancias atuais, os kits de teste de anticorpos COVID-19 n\u00e3o s\u00e3o vigorosamente avaliados por sua sensibilidade e especificidade.<\/span> Portanto, h\u00e1 algumas preocupa\u00e7\u00f5es sobre a confiabilidade dos testes de anticorpos, particularmente no que diz respeito ao n\u00famero de falsos negativos, que poderiam inflar a propaga\u00e7\u00e3o ou falsos positivos que poderiam indicar estimativas erradas da taxa de infec\u00e7\u00e3o.<\/span><\/p>\n

Leve uma mensagem para casa<\/i><\/strong><\/p>\n

Atualmente, a melhor maneira de deter a infec\u00e7\u00e3o pela COVID-19 \u00e9 atrav\u00e9s do distanciamento social. Al\u00e9m disso, a higiene pessoal e a imunidade s\u00e3o essenciais para a prote\u00e7\u00e3o contra a COVID-19, especialmente quando retomamos nosso estilo de vida rotineiro.<\/span><\/p>\n

Embora o teste qualitativo de anticorpos possa n\u00e3o ser confi\u00e1vel para conferir ao 100% prote\u00e7\u00e3o contra a COVID-19, seu uso \u00e9 muito \u00fatil no gerenciamento geral da pandemia.<\/span><\/p>","protected":false},"excerpt":{"rendered":"

A doen\u00e7a coronav\u00edrus \u00e9 uma doen\u00e7a infecciosa respirat\u00f3ria preliminar causada por um novo coronav\u00edrus tamb\u00e9m chamado de COVID-19 ou SARS-CoV-2. Foi declarada como uma pandemia global pela Organiza\u00e7\u00e3o Mundial da Sa\u00fade (OMS) em 11 de mar\u00e7o de 2020, afetando mais de 210 pa\u00edses e territ\u00f3rios ao redor do mundo. Como sabemos, o v\u00edrus COVID-19 se espalhou principalmente<\/p>\n

Leia mais<\/a><\/div>","protected":false},"author":12,"featured_media":7767,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[558],"tags":[],"acf":[],"yoast_head":"\nRole of Anti-COVID-19 antibody testing in the management of pandemic - The Kolabtree Blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.kolabtree.com\/blog\/pt\/role-of-anti-covid-19-antibody-testing-in-the-management-of-pandemic\/\" \/>\n<meta property=\"og:locale\" content=\"pt_BR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Role of Anti-COVID-19 antibody testing in the management of pandemic\" \/>\n<meta property=\"og:description\" content=\"The coronavirus disease is preliminary a respiratory infectious disease caused by a novel coronavirus also termed as COVID-19 or SARS-CoV-2. 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