{"id":7723,"date":"2020-06-01T13:28:13","date_gmt":"2020-06-01T13:28:13","guid":{"rendered":"https:\/\/www.kolabtree.com\/blog\/?p=7723"},"modified":"2020-06-01T13:39:27","modified_gmt":"2020-06-01T13:39:27","slug":"covid-19-and-maternal-health-is-the-virus-a-threat","status":"publish","type":"post","link":"https:\/\/www.kolabtree.com\/blog\/pt\/covid-19-and-maternal-health-is-the-virus-a-threat\/","title":{"rendered":"COVID-19 e a sa\u00fade materna: o v\u00edrus \u00e9 uma amea\u00e7a?"},"content":{"rendered":"

Laura Moro<\/a>, pesquisadora biom\u00e9dica experiente e escritor cient\u00edfico<\/a>discute o efeito da COVID-19 sobre a gravidez e a sa\u00fade materna.\u00a0<\/em><\/p>\n

A doen\u00e7a coronav\u00edrus 2019 (COVID-19), causada pela s\u00edndrome respirat\u00f3ria aguda grave coronav\u00edrus 2 (SARS-CoV-2), continua a crescer em todo o mundo, sendo a Europa e os EUA agora os epicentros da pandemia. Desde 15 de abril, h\u00e1 quase dois milh\u00f5es de casos declarados e mais de 123.000 mortes em todo o mundo, com muitos pa\u00edses sofrendo transmiss\u00e3o comunit\u00e1ria (1). <\/span>Embora a maioria das infec\u00e7\u00f5es com SRA-CoV-2 sejam leves, os idosos e pessoas com comorbidades - incluindo doen\u00e7as cardiovasculares e respirat\u00f3rias, hipertens\u00e3o, diabetes e c\u00e2ncer - correm um risco maior de doen\u00e7as graves e morte (2,3).\u00a0<\/span><\/p>\n

As mulheres gr\u00e1vidas s\u00e3o particularmente vulner\u00e1veis a v\u00e1rias doen\u00e7as infecciosas que podem causar resultados adversos tanto maternais quanto fetais (4-6). As adapta\u00e7\u00f5es imunol\u00f3gicas e fisiol\u00f3gicas que ocorrem durante a gesta\u00e7\u00e3o est\u00e3o por tr\u00e1s deste risco aumentado (7). Durante surtos anteriores causados pela SRA-CoV e pela S\u00edndrome Respirat\u00f3ria do Oriente M\u00e9dio CoV (MERS-CoV), v\u00e1rias mulheres gr\u00e1vidas adquiriram a infec\u00e7\u00e3o. A SRA-CoV - uma 'prima' da SRA-CoV-2 - foi associada a doen\u00e7a materna grave, morte materna, aborto espont\u00e2neo, restri\u00e7\u00e3o severa do crescimento intra-uterino, parto prematuro e complica\u00e7\u00f5es gastrointestinais com risco de vida no rec\u00e9m-nascido (8). Entre os poucos casos conhecidos de mulheres gr\u00e1vidas infectadas pelo MERS-CoV, foram relatados v\u00e1rios \u00f3bitos maternos e neonatais e natimortos (9).<\/span><\/p>\n

As comunidades cient\u00edfica e m\u00e9dica est\u00e3o colocando um esfor\u00e7o imenso em compartilhar informa\u00e7\u00f5es sobre a COVID-19. Existem atualmente mais de 20 relatos de casos publicados e s\u00e9ries de casos apresentando mulheres gr\u00e1vidas infectadas pelo SARS-CoV-2 e alguns estudos de controle de casos, a maioria deles da China. As mulheres gr\u00e1vidas parecem apresentar uma apresenta\u00e7\u00e3o de doen\u00e7a semelhante \u00e0s suas cong\u00eaneres n\u00e3o gr\u00e1vidas, sendo a febre e a tosse os sintomas mais freq\u00fcentes (10). N\u00e3o h\u00e1 evid\u00eancias de transmiss\u00e3o vertical do v\u00edrus de m\u00e3es infectadas para o feto (11), embora alguns rec\u00e9m-nascidos tenham apresentado resultados positivos algumas horas ap\u00f3s o nascimento (12,13). V\u00e1rios resultados adversos maternos e fetais foram relatados, incluindo parto prematuro, ang\u00fastia fetal, baixo peso ao nascer e sintomas respirat\u00f3rios no rec\u00e9m-nascido, entre outros (10,14). O parto prematuro, a principal causa de morte em crian\u00e7as menores de cinco anos, aparece como o resultado adverso mais comum da gravidez causada pelos coronav\u00edrus (15). Assim, as futuras m\u00e3es devem ser consideradas nas estrat\u00e9gias de preven\u00e7\u00e3o e tratamento contra a COVID-19, garantindo a seguran\u00e7a de medicamentos e vacinas durante a gravidez.<\/span><\/p>\n

As mulheres gr\u00e1vidas e rec\u00e9m-nascidas em ambientes de poucos recursos, assim como as refugiadas e aquelas em zonas de conflito, constituem uma das popula\u00e7\u00f5es mais vulner\u00e1veis, e s\u00e3o urgentemente necess\u00e1rios esfor\u00e7os concertados para garantir sua sa\u00fade e seu bem-estar. Os servi\u00e7os de sa\u00fade - incluindo, por exemplo, a quimiopreven\u00e7\u00e3o da mal\u00e1ria para mulheres gr\u00e1vidas - devem ser garantidos durante a pandemia, evitando o efeito perturbador de surtos anteriores de doen\u00e7as (16).\u00a0<\/span><\/p><\/blockquote>\n

O OMS<\/a>(17), assim como outras organiza\u00e7\u00f5es internacionais e autoridades sanit\u00e1rias nacionais, emitiram recomenda\u00e7\u00f5es interinas para o cuidado e gest\u00e3o de mulheres gr\u00e1vidas infectadas pelo SARS-CoV-2. Estas recomenda\u00e7\u00f5es desaconselham partos desnecess\u00e1rios de cesariana e encorajam o aleitamento materno, se poss\u00edvel. <\/span>Embora ainda tenhamos poucos dados sobre o impacto da COVID-19 em mulheres gr\u00e1vidas e rec\u00e9m-nascidas, <\/span>triagem sistem\u00e1tica e acompanhamento cuidadoso de qualquer suspeita de infec\u00e7\u00e3o pelo SARS-CoV-2 <\/span>durante a gravidez<\/span> \u00e9 crucial para garantir a sa\u00fade maternal.<\/span><\/p>\n

Sobre o autor<\/strong>\"\"<\/a><\/p>\n

Laura Moro, PhD, is a researcher and science & health writer. She is particularly interested in infectious diseases, global and planetary health. She conducted pesquisa<\/a> for several years on infectious diseases affecting pregnant women in Sub-Saharan Africa.\u00a0<\/span>CONDUZIR LAURA<\/a><\/p><\/blockquote>\n

Necessidade de consultar um especialista em coronav\u00edrus? Fale com Pesquisadores da COVID-19<\/a> diretamente em Kolabtree. Contrate escritores cient\u00edficos<\/a> para ajuda na verifica\u00e7\u00e3o de informa\u00e7\u00f5es e reda\u00e7\u00e3o cient\u00edfica. Contato especialistas em gravidez<\/a> e parto.\u00a0 Comece agora<\/a><\/strong><\/p>\n

Refer\u00eancias<\/b><\/p>\n

    \n
  1. Organiza\u00e7\u00e3o Mundial da Sa\u00fade. Coronavirus disease 2019 (COVID-19) Situation Report-86 (15 de abril).\u00a0<\/span><\/li>\n
  2. Yang J, Zheng Y, Gou X, Pu K, Chen Z, Guo Q, et al. Preval\u00eancia de comorbidades na nova infec\u00e7\u00e3o pelo coronav\u00edrus Wuhan (COVID-19): uma revis\u00e3o sistem\u00e1tica e uma meta-an\u00e1lise. Int J Infect Dis. 2020 Mar 12.\u00a0<\/span><\/li>\n
  3. Wu Z, McGoogan JM. Caracter\u00edsticas e Li\u00e7\u00f5es Importantes da Doen\u00e7a de Coronavirus 2019 (COVID-19) Surto na China. JAMA. 2020 Fev 24.\u00a0<\/span><\/li>\n
  4. Thompson JM, Eick SM, Dailey C, Dale AP, Mehta M, Nair A, et al. Rela\u00e7\u00e3o entre Mal\u00e1ria Associada \u00e0 Gravidez e Resultados da Gravidez Adversa: uma Revis\u00e3o Sistem\u00e1tica e Meta-An\u00e1lise. J Trop Pediatr. 2019 Out. 10.\u00a0<\/span><\/li>\n
  5. Shi T, Huang L-J, Xiong Y-Q, Zhong Y-Y, Yang J-J, Fu T, et al. O risco do v\u00edrus do herpes simples e da infec\u00e7\u00e3o pelo citomegalov\u00edrus humano durante a gravidez em caso de resultados adversos na gravidez: Uma meta-an\u00e1lise. J Clin Virol. 2018 Jul;104:48-55.\u00a0<\/span><\/li>\n
  6. Mertz D, Geraci J, Winkup J, Gessner BD, Ortiz JR, Loeb M. Gravidez como um fator de risco para resultados graves da infec\u00e7\u00e3o pelo v\u00edrus da influenza: Uma revis\u00e3o sistem\u00e1tica e uma meta-an\u00e1lise de estudos observacionais. Vacina. 2017 Jan 23;35(4):521-8.\u00a0<\/span><\/li>\n
  7. Kourtis AP, Leia JS, Jamieson DJ. Gravidez e Infec\u00e7\u00e3o. N Engl J Med. Massachusetts Medical Society ; 2014 Jun 5;370(23):2211-8.\u00a0<\/span><\/li>\n
  8. Wong SF, Chow KM, Leung TN, Ng WF, Ng TK, Shek CC, et al. Gravidez e resultados perinatais de mulheres com s\u00edndrome respirat\u00f3ria aguda severa. Am J Obstet Gynecol. 2004 Jul;191(1):292-7.\u00a0<\/span><\/li>\n
  9. Alfaraj SH, Al-Tawfiq JA, Memish ZA. S\u00edndrome Respirat\u00f3ria do Oriente M\u00e9dio Coronavirus (MERS-CoV) infec\u00e7\u00e3o durante a gravidez: Relat\u00f3rio de dois casos e revis\u00e3o da literatura. J Microbiol Immunol Infect. 2019 Jun;52(3):501-3.\u00a0<\/span><\/li>\n
  10. Zaigham M, Andersson O. Resultados maternos e perinatais com a COVID-19: uma revis\u00e3o sistem\u00e1tica de 108 gesta\u00e7\u00f5es. Esc\u00e2ndalo Acta Obstet Gynecol. 2020 Abr 7.<\/span><\/li>\n
  11. Karimi-Zarchi M, Neamatzadeh H, Dastgheib SA, Abbasi H, Mirjalili SR, Behforouz A, et al. Transmiss\u00e3o vertical da Doen\u00e7a do Coronav\u00edrus 19 (COVID-19) de M\u00e3es Gr\u00e1vidas Infectadas para Neonatos: Uma Revis\u00e3o. Pathol Fetal Pediatra. 2020 Abr 2;1-5.\u00a0<\/span><\/li>\n
  12. Zeng L, Xia S, Yuan W, Yan K, Xiao F, Shao J, et al. Infec\u00e7\u00e3o Neonatal Precoce com SARS-CoV-2 em 33 Neonatos nascidos para M\u00e3es com COVID-19 em Wuhan, China. JAMA Pediatr. 2020 Mar 26.\u00a0<\/span><\/li>\n
  13. Dong L, Tian J, He S, Zhu C, Wang J, Liu C, et al. Poss\u00edvel transmiss\u00e3o vertical da SARS-CoV-2 de uma m\u00e3e infectada para seu rec\u00e9m-nascido. JAMA. 2020 Mar 26.\u00a0<\/span><\/li>\n
  14. Li N, Han L, Peng M, Lv Y, Ouyang Y, Liu K, et al. Resultados maternos e neonatais de mulheres gr\u00e1vidas com pneumonia COVID-19: um estudo de caso-controle. Dis. Clin Infect Dis. 2020 Mar 30.\u00a0<\/span><\/li>\n
  15. Di Mascio D, Khalil A, Saccone G, Rizzo G, Buca D, Liberati M, et al. Resultado das infec\u00e7\u00f5es do espectro do Coronav\u00edrus (SARS, MERS, COVID 1 -19) durante a gravidez: uma revis\u00e3o sistem\u00e1tica e uma meta-an\u00e1lise. Am J Obstet Gynecol MFM. 2020 Mar 25;100107.\u00a0<\/span><\/li>\n
  16. Organiza\u00e7\u00e3o Mundial da Sa\u00fade. A OMS insta os pa\u00edses a garantir a continuidade dos servi\u00e7os contra a mal\u00e1ria no contexto da pandemia COVID-19 [Internet]. [citado 2020 Abr 2]. Dispon\u00edvel em: https:\/\/www.who.int\/news-room\/detail\/25-03-2020-who-urges-countries-to-ensure-the-continuity-of-malaria-services-in-the-context-of-the-covid-19-pandemic<\/span><\/li>\n
  17. Organiza\u00e7\u00e3o Mundial da Sa\u00fade. Gerenciamento cl\u00ednico de infec\u00e7\u00f5es respirat\u00f3rias agudas graves quando h\u00e1 suspeita da COVID-19. Orienta\u00e7\u00e3o interina. 2020.\u00a0<\/span><\/li>\n<\/ol>\n

     <\/p>","protected":false},"excerpt":{"rendered":"

    Laura Moro, experienced biomedical researcher and science writer, discusses the effect of COVID-19 on pregnancy and maternal health.\u00a0 Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), continues to escalate worldwide, with Europe and the USA now the epicentres of the pandemic. As of April 15, there are almost two million<\/p>\n

    Leia mais<\/a><\/div>","protected":false},"author":12,"featured_media":7726,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[558,443],"tags":[],"acf":[],"yoast_head":"\nCOVID-19 and maternal health: is the virus a threat? - The Kolabtree Blog<\/title>\n<meta name=\"description\" content=\"How does COVID-19 affect pregnant women and maternal health? 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