{"id":4989,"date":"2018-11-21T12:19:49","date_gmt":"2018-11-21T12:19:49","guid":{"rendered":"https:\/\/blog.kolabtree.com\/?p=4989"},"modified":"2018-11-22T12:09:46","modified_gmt":"2018-11-22T12:09:46","slug":"15-ways-to-reduce-sample-size-in-clinical-trials-infographic","status":"publish","type":"post","link":"https:\/\/www.kolabtree.com\/blog\/pt\/15-ways-to-reduce-sample-size-in-clinical-trials-infographic\/","title":{"rendered":"[INFOGR\u00c1FICO] 15 maneiras de reduzir o tamanho da amostra em ensaios cl\u00ednicos"},"content":{"rendered":"

Os custos dos ensaios cl\u00ednicos aumentaram na \u00faltima d\u00e9cada, com relat\u00f3rios recentes afirmando que, de 2008 a 2013, o custo m\u00e9dio por paciente aumentou em $23.600. Um grande contribuinte para o custo de um ensaio cl\u00ednico<\/a> est\u00e1 sujeita ao recrutamento e aos custos de pessoal associados.\u00a0<\/span>Portanto, examinar cada oportunidade de reduzir o tamanho da amostra para um estudo \u00e9 um passo importante e necess\u00e1rio no desenvolvimento de medicamentos.<\/span>
\n<\/span><\/p>\n

A redu\u00e7\u00e3o do tamanho da amostra sem perda de pot\u00eancia pode ser realizada por um de tr\u00eas princ\u00edpios.<\/span><\/p>\n

Nesta infografia, examinamos estas e apresentamos 15 maneiras pelas quais os pesquisadores podem reduzir o tamanho da amostra em ensaios cl\u00ednicos.<\/span><\/p>\n

\"\"<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
15 maneiras de reduzir o tamanho da amostra em ensaios cl\u00ednicos<\/b><\/td>\n<\/tr>\n
#<\/b><\/td>\nM\u00e9todo<\/b><\/td>\nPotencial\u00a0<\/b>Redu\u00e7\u00e3o<\/b><\/td>\n<\/tr>\n
1<\/span><\/td>\nAjuste para Vari\u00e1veis Independentes na An\u00e1lise Final<\/span><\/td>\n0 – 10%<\/span><\/td>\n<\/tr>\n
2<\/span><\/td>\nEstratificar os Pacientes<\/span><\/td>\n0 - 20%<\/span><\/td>\n<\/tr>\n
3<\/span><\/td>\nEnrique\u00e7a os Pacientes<\/span><\/td>\n0 - 20%<\/span><\/td>\n<\/tr>\n
4<\/span><\/td>\nUsar resposta sustentada<\/span><\/td>\n0 - 25%<\/span><\/td>\n<\/tr>\n
5<\/span><\/td>\nUsar compara\u00e7\u00f5es em pares<\/span><\/td>\n0 - 30%<\/span><\/td>\n<\/tr>\n
6<\/span><\/td>\nAn\u00e1lise de freq\u00fc\u00eancia de uso<\/span><\/td>\n0 - 40%<\/span><\/td>\n<\/tr>\n
7<\/span><\/td>\nUsar t\u00e9cnica estat\u00edstica que corresponda \u00e0 curva de resposta antecipada<\/span><\/td>\n0 - 50%<\/span><\/td>\n<\/tr>\n
8<\/span><\/td>\nUtilizar pontos terminais de substitui\u00e7\u00e3o<\/span><\/td>\n0 - 70%<\/span><\/td>\n<\/tr>\n
9<\/span><\/td>\nAumentar a taxa de eventos<\/span><\/td>\n0 – 90%<\/span><\/td>\n<\/tr>\n
10<\/span><\/td>\nRealizar um teste cl\u00ednico rigoroso<\/span><\/td>\n5 – 20%<\/span><\/td>\n<\/tr>\n
11<\/span><\/td>\nUse o corte ideal para o ponto final bin\u00e1rio<\/span><\/td>\n10 - 30%<\/span><\/td>\n<\/tr>\n
12<\/span><\/td>\nUse uma Vari\u00e1vel Cont\u00ednua<\/span><\/td>\n10 - 40%<\/span><\/td>\n<\/tr>\n
13<\/span><\/td>\nUse Design Adaptativo<\/span><\/td>\n10 - 50%<\/span><\/td>\n<\/tr>\n
14<\/span><\/td>\nUse os estudos da Crossover<\/span><\/td>\n50 - 70%<\/span><\/td>\n<\/tr>\n
15<\/span><\/td>\nUsar Desenhos Fatoriais<\/span><\/td>\n50 - 75%<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

D\u00ea uma olhada no guia ampliado sobre o <\/span>nQuery Tamanho da amostra Software website<\/span><\/a>.<\/span><\/p>\n

Precisa de ajuda para projetar um ensaio cl\u00ednico? Contratar especialistas qualificados<\/a> sobre Kolabtree que pode ajud\u00e1-lo com m\u00e9todos de coleta de dados, an\u00e1lise estat\u00edstica e valida\u00e7\u00e3o, e otimiza\u00e7\u00e3o do projeto do estudo. \u00c9 gr\u00e1tis para postar seu projeto e obter or\u00e7amentos.
\n<\/b><\/p>\n

 <\/p>","protected":false},"excerpt":{"rendered":"

Clinical trial costs have surged over the past decade, with recent reports stating that from 2008 to 2013, the average cost per patient increased by $23,600. A major contributor to the cost of a clinical trial is subject recruitment and the associated staff costs.\u00a0So, examining every opportunity to reduce the sample size for a study<\/p>\n

Leia mais<\/a><\/div>","protected":false},"author":75,"featured_media":5048,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[443,435],"tags":[467,464,459,454,463,458,455,462],"acf":[],"yoast_head":"\n[INFOGRAPHIC] 15 Ways to Reduce Sample Size In Clinical Trials - The Kolabtree Blog<\/title>\n<meta name=\"description\" content=\"In this infographic we examine 15 ways and oppportunities for researchers to reduce sample size in clinical trials and save costs.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.kolabtree.com\/blog\/pt\/15-ways-to-reduce-sample-size-in-clinical-trials-infographic\/\" \/>\n<meta property=\"og:locale\" content=\"pt_BR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"[INFOGRAPHIC] 15 Ways to Reduce Sample Size In Clinical Trials\" \/>\n<meta property=\"og:description\" content=\"In this infographic we examine 15 ways and oppportunities for researchers to reduce sample size in clinical trials and save costs.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.kolabtree.com\/blog\/pt\/15-ways-to-reduce-sample-size-in-clinical-trials-infographic\/\" \/>\n<meta property=\"og:site_name\" content=\"The Kolabtree Blog\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/kolabtree\" \/>\n<meta property=\"article:published_time\" content=\"2018-11-21T12:19:49+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2018-11-22T12:09:46+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.kolabtree.com\/blog\/wp-content\/uploads\/2018\/11\/computer-1149148_1280-1.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1280\" \/>\n\t<meta property=\"og:image:height\" content=\"720\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Laura Tobin\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@kolabtree\" \/>\n<meta name=\"twitter:site\" content=\"@kolabtree\" \/>\n<meta name=\"twitter:label1\" content=\"Escrito por\" \/>\n\t<meta name=\"twitter:data1\" content=\"Laura Tobin\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. tempo de leitura\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minuto\" \/>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"[INFOGRAPHIC] 15 Ways to Reduce Sample Size In Clinical Trials - 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