{"id":9205,"date":"2021-06-07T05:59:33","date_gmt":"2021-06-07T05:59:33","guid":{"rendered":"https:\/\/www.kolabtree.com\/blog\/?p=9205"},"modified":"2021-09-30T12:07:09","modified_gmt":"2021-09-30T12:07:09","slug":"vibhor-mishra-assembly-of-a-dsrna-synthesizing-complex","status":"publish","type":"post","link":"https:\/\/www.kolabtree.com\/blog\/ja\/vibhor-mishra-assembly-of-a-dsrna-synthesizing-complex\/","title":{"rendered":"Vibhor Mishra: dsRNA\u5408\u6210\u8907\u5408\u4f53\u306e\u7d44\u307f\u7acb\u3066"},"content":{"rendered":"

Vibhor Mishra<\/a>, freelance scientist on Kolabtree, has recently published a \u30ea\u30b5\u30fc\u30c1<\/a> paper titled,<\/p>\n

\"\u4e8c\u672c\u9396RNA\u5408\u6210\u8907\u5408\u4f53\u306e\u7d44\u307f\u7acb\u3066RNA-DEPENDENT RNA POLYMERASE 2\u306fNUCLEAR RNA POLYMERASE IV\u306e\u6700\u5927\u30b5\u30d6\u30e6\u30cb\u30c3\u30c8\u306b\u63a5\u89e6\u3059\u308b\"<\/p><\/blockquote>\n

\u4ee5\u4e0b\u306f\u3001\u305d\u306e\u8a18\u4e8b\u306e\u8981\u65e8\u3067\u3042\u308b\u3002<\/p>\n

\u690d\u7269\u3067\u306f\u3001\u30c8\u30e9\u30f3\u30b9\u30dd\u30be\u30f3\u3084DNA\u30a6\u30a4\u30eb\u30b9\u306a\u3069\u306e\u5229\u5df1\u7684\u306a\u907a\u4f1d\u8981\u7d20\u306e\u8ee2\u5199\u306f\u3001RNA\u306b\u3088\u308bDNA\u30e1\u30c1\u30eb\u5316\u306b\u3088\u3063\u3066\u6291\u5236\u3055\u308c\u308b\u3002\u3053\u306e\u904e\u7a0b\u306f\u300124nt\u306e\u77ed\u5e72\u6e09\u6027RNA\uff08siRNA\uff09\u306b\u3088\u3063\u3066\u5c0e\u304b\u308c\u3001\u305d\u306e\u4e8c\u672c\u9396\u306e\u524d\u99c6\u4f53\u306fDNA\u4f9d\u5b58\u6027\u306eNUCLEAR RNA POLYMERASE IV (Pol IV) \u3068RNA-DEPENDENT RNA POLYMERASE 2 (RDR2) \u306b\u3088\u308a\u5408\u6210\u3055\u308c\u308b\u3002Pol IV\u3068RDR2\u306f\u5171\u514d\u75ab\u6c88\u964d\u3057\u3001\u4e21\u8005\u306e\u6d3b\u6027\u306f\u7dca\u5bc6\u306b\u7d50\u5408\u3057\u3066\u3044\u308b\u304c\u3001\u305d\u306e\u7d50\u5408\u306e\u6839\u62e0\u306f\u4e0d\u660e\u3067\u3042\u3063\u305f\u3002\u4eca\u56de\u3001\u6211\u3005\u306f\u3001RDR2\u306e\u6d3b\u6027\u90e8\u4f4d\u8fd1\u508d\u306e\u9818\u57df\u304c\u3001Pol IV\u306e12\u500b\u306e\u30b5\u30d6\u30e6\u30cb\u30c3\u30c8\u306e\u3046\u3061\u6700\u5927\u306e\u89e6\u5a92\u30b5\u30d6\u30e6\u30cb\u30c3\u30c8\u3067\u3042\u308bNRPD1\u3068\u63a5\u89e6\u3057\u3066\u3044\u308b\u3053\u3068\u3092\u660e\u3089\u304b\u306b\u3057\u305f\u3002\u3053\u306e2\u3064\u306e\u9175\u7d20\u306e\u89e6\u5a92\u9818\u57df\u306e\u63a5\u89e6\u306f\u3001RDR2\u304cPol IV\u8ee2\u5199\u7523\u7269\u306e\u904a\u96e23\u2032\u672b\u7aef\u3068\u8fc5\u901f\u306b\u7d50\u5408\u3057\u3001\u3053\u308c\u3089\u306e\u4e00\u672c\u9396\u8ee2\u5199\u7523\u7269\u3092\u4e8c\u672c\u9396RNA\uff08dsRNA\uff09\u306b\u5909\u63db\u3059\u308b\u4f4d\u7f6e\u306b\u3042\u308b\u3053\u3068\u3092\u793a\u5506\u3059\u308b\u3082\u306e\u3067\u3042\u3063\u305f\u3002<\/p><\/blockquote>\n

PNAS\u306b\u63b2\u8f09\u3055\u308c\u305f\u5168\u6587\u3092\u3054\u89a7\u304f\u3060\u3055\u3044\u3002\u00a0<\/strong><\/a><\/p>\n

\u306e\u3067\u3059\u3002 \u51fa\u7248\u304c\u63a8\u5968\u3055\u308c\u307e\u3057\u305f<\/a> \u30c6\u30ad\u30b5\u30b9\u5927\u5b66\u30aa\u30fc\u30b9\u30c6\u30a3\u30f3\u6821\u306eZ Jeffrey Chen\u535a\u58eb\u306b\u3088\u308bFacultyOpinions\u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002<\/p><\/blockquote>\n

Vibhor Mishra<\/a> \u306f\u3001\u30bb\u30f3\u30c8\u30fb\u30b8\u30e5\u30fc\u30c9\u5c0f\u5150\u7814\u7a76\u75c5\u9662\u306e\u79d1\u5b66\u8005\u3067\u3042\u308a\u3001\u30b5\u30a4\u30a2\u30c9\u30d0\u30a4\u30b6\u30fc\u306e\u5171\u540c\u8a2d\u7acb\u8005\u3067\u3059\u3002
\n\u79d1\u5b66\u30b3\u30f3\u30b5\u30eb\u30bf\u30f3\u30c8\u4f1a\u793e\u3002\u5206\u5b50\u69cb\u9020\u751f\u7269\u5b66\u3067\u535a\u58eb\u53f7\u3092\u53d6\u5f97\u3002Vibhor\u306f
\n\u907a\u4f1d\u5b50\u30b5\u30a4\u30ec\u30f3\u30b7\u30f3\u30b0\u306b\u95a2\u4e0e\u3059\u308b\u5206\u5b50\u5236\u5fa1\u56e0\u5b50\u306e\u5185\u90e8\u69cb\u9020\u3092\u89e3\u660e\u3059\u308b\u3053\u3068\u306b10\u5e74\u9593\u53d6\u308a\u7d44\u3093\u3067\u304d\u307e\u3057\u305f\u3002\u5f7c\u306e
\n\u672c\u7814\u7a76\u3067\u306f
\n\u4e16\u754c\u7684\u306b\u5c0f\u5150\u6b7b\u4ea1\u7387\u306e\u4e0a\u4f4d\u3092\u5360\u3081\u308b\u5c0f\u5150\u304c\u3093\u3092\u3001\u3055\u307e\u3056\u307e\u306a\u7a2e\u985e\u306e\u304c\u3093\u304c\u5360\u3081\u3066\u3044\u307e\u3059\u3002\u5f7c\u306f\u3053\u3046\u8003\u3048\u3066\u3044\u307e\u3059\u3002
\n\u304c\u3093\u3092\u5f15\u304d\u8d77\u3053\u3059\u8981\u56e0\u306e\u8907\u96d1\u306a\u5206\u5b50\u30e1\u30ab\u30cb\u30ba\u30e0\u306e\u7814\u7a76\u304c\u6025\u52d9\u3067\u3042\u308b
\n\u3053\u306e\u53e4\u304f\u304b\u3089\u3042\u308b\u554f\u984c\u306b\u65b0\u305f\u306a\u89e3\u6c7a\u7b56\u3092\u898b\u51fa\u3059\u305f\u3081\u306b\u3002Vibhor\u306f\u3001\u7279\u96c6\u8a18\u4e8b\u57f7\u7b46\u8005\u3001\u6e96\u6559\u6388\u3067\u3059\u3002
\n\u307e\u305f\u3001\u3044\u304f\u3064\u304b\u306e\u79d1\u5b66\u96d1\u8a8c\u304a\u3088\u3073\u52a9\u6210\u91d1\u306e\u81e8\u6642\u5be9\u67fb\u54e1\u3082\u52d9\u3081\u3066\u3044\u307e\u3059\u3002
\n\u30d1\u30cd\u30eb\u306b\u8868\u793a\u3055\u308c\u307e\u3059\u3002<\/p>\n

Kolabtree\u3067\u306f\u3001Vibhor\u306f\u6cbb\u7642\u7528\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u8a2d\u8a08\u3068\u30a8\u30f3\u30b8\u30cb\u30a2\u30ea\u30f3\u30b0\u306e\u696d\u754c\u30ea\u30fc\u30c0\u30fc\u3068\u306e\u3064\u306a\u304c\u308a\u3092\u6c42\u3081\u3066\u3044\u307e\u3059\u3002\u5f7c\u306f\u3001\u30bf\u30f3\u30d1\u30af\u8cea\/\u30da\u30d7\u30c1\u30c9\u306e\u8a2d\u8a08\u3001\u30a8\u30f3\u30b8\u30cb\u30a2\u30ea\u30f3\u30b0\u3001\u958b\u767a\u3001\u751f\u7523\u3001\u7279\u6027\u8a55\u4fa1\u306b\u95a2\u3059\u308b\u5c02\u9580\u7684\u306a\u30bd\u30ea\u30e5\u30fc\u30b7\u30e7\u30f3\u3092\u63d0\u4f9b\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u30029\u5e74\u9593\u306b\u308f\u305f\u308a\u3001\u5171\u540c\u30d7\u30ed\u30b8\u30a7\u30af\u30c8\u306b\u304a\u3044\u3066\u7814\u7a76\u8005\u3092\u6307\u5c0e\u30fb\u7ba1\u7406\u3057\u300112\u4ef6\u306e\u51fa\u7248\u7269\u3068$1\u5343\u4e07\u30c9\u30eb\u306e\u7814\u7a76\u52a9\u6210\u91d1\u3092\u3082\u305f\u3089\u3057\u305f\u7d4c\u9a13\u304c\u3042\u308b\u30025\u3064\u306e\u56fd\u969b\u7684\u306a\u79d1\u5b66\u96d1\u8a8c\u3068\u67fb\u8aad\u4ed8\u304d\u79d1\u5b66\u51fa\u7248\u7269\u3067\u72ec\u81ea\u306b\u7814\u7a76\u5185\u5bb9\u3092\u4f1d\u9054\/\u767a\u8868\u3057\u3066\u3044\u308b\u3002 \u3053\u3053\u306b\u76f8\u8ac7\u3059\u308b<\/strong><\/a><\/p>","protected":false},"excerpt":{"rendered":"

Kolabtree\u306e\u30d5\u30ea\u30fc\u30e9\u30f3\u30b9\u30fb\u30b5\u30a4\u30a8\u30f3\u30c6\u30a3\u30b9\u30c8\u3001Vibhor Mishra\u306f\u3001\u6700\u8fd1\u300cAssembly of a dsRNA synthesizing complex\u300d\u3068\u984c\u3059\u308b\u7814\u7a76\u8ad6\u6587\u3092\u767a\u8868\u3057\u307e\u3057\u305f\u3002RNA-DEPENDENT RNA POLYMERASE 2\u306fNUCLEAR RNA POLYMERASE IV\u306e\u6700\u5927\u30b5\u30d6\u30e6\u30cb\u30c3\u30c8\u306b\u63a5\u89e6\u3059\u308b\u300d\u3068\u3044\u3046\u8ad6\u6587\u306e\u8981\u65e8\u306f\u4ee5\u4e0b\u306e\u901a\u308a\u3067\u3059\u3002\u690d\u7269\u3067\u306f\u3001\u30c8\u30e9\u30f3\u30b9\u30dd\u30be\u30f3\u3084DNA\u30a6\u30a4\u30eb\u30b9\u306a\u3069\u306e\u5229\u5df1\u7684\u306a\u907a\u4f1d\u8981\u7d20\u306e\u8ee2\u5199\u306f\u3001RNA\u306b\u3088\u308bDNA\u30e1\u30c1\u30eb\u5316\u306b\u3088\u3063\u3066\u6291\u5236\u3055\u308c\u308b\u3002\u3053\u306e\u30d7\u30ed\u30bb\u30b9\u306f\u300124nt\u306e\u77ed\u5e72\u6e09\u6027RNA\uff08siRNA\uff09\u306b\u3088\u3063\u3066\u5c0e\u304b\u308c\u308b\u3002\u305d\u306e\u4e8c\u672c\u9396\u306e\u524d\u99c6\u4f53\u306f\u3001DNA\u4f9d\u5b58\u6027\u306eNUCLEAR RNA POLYMERASE IV (Pol IV) \u3068 RNA-DEPENDENT RNA POLYMERASE 2 (RDR2) \u306b\u3088\u3063\u3066\u5408\u6210\u3055\u308c\u3066\u3044\u308b\u3002Pol IV\u3068RDR2\u306f\u5171\u514d\u75ab\u6c88\u964d\u3057\u3001\u4e21\u8005\u306e\u6d3b\u6027\u306f\u7dca\u5bc6\u306b\u7d50\u5408\u3057\u3066\u3044\u308b\u304c\u3001\u305d\u306e\u7d50\u5408\u306e\u6839\u62e0\u306f\u4e0d\u660e\u3067\u3042\u3063\u305f\u3002\u4eca\u56de\u3001\u6211\u3005\u306f<\/p>\n

\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/div>","protected":false},"author":12,"featured_media":9208,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[662,661],"tags":[],"acf":[],"yoast_head":"\nVibhor Mishra: Assembly of a dsRNA synthesizing complex<\/title>\n<meta name=\"description\" content=\"Kolabtree scientist Vibhor Mishra's latest publication on assembly of a dsRNA synthesizing complex has been published in PNAS.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.kolabtree.com\/blog\/ja\/vibhor-mishra-assembly-of-a-dsrna-synthesizing-complex\/\" \/>\n<meta property=\"og:locale\" content=\"ja_JP\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Vibhor Mishra: Assembly of a dsRNA synthesizing complex\" \/>\n<meta property=\"og:description\" content=\"Kolabtree scientist Vibhor Mishra's latest publication on assembly of a dsRNA synthesizing complex has been published in PNAS.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.kolabtree.com\/blog\/ja\/vibhor-mishra-assembly-of-a-dsrna-synthesizing-complex\/\" \/>\n<meta property=\"og:site_name\" content=\"The Kolabtree Blog\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/kolabtree\" \/>\n<meta property=\"article:published_time\" content=\"2021-06-07T05:59:33+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2021-09-30T12:07:09+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.kolabtree.com\/blog\/wp-content\/uploads\/2021\/06\/Blog-headertemplate-1078x516-5.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1078\" \/>\n\t<meta property=\"og:image:height\" content=\"516\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Ramya Sriram\" \/>\n<meta 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