{"id":2396,"date":"2017-09-06T06:24:23","date_gmt":"2017-09-06T06:24:23","guid":{"rendered":"https:\/\/www.kolabtree.com\/blog\/?p=2396"},"modified":"2020-11-09T05:05:05","modified_gmt":"2020-11-09T05:05:05","slug":"cell-lines-challenges-applications","status":"publish","type":"post","link":"https:\/\/www.kolabtree.com\/blog\/ja\/cell-lines-challenges-applications\/","title":{"rendered":"\u7d30\u80de\u682a - \u8ab2\u984c\u3001\u5fdc\u7528\u3001\u7814\u7a76\u7bc4\u56f2"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_45_1 counter-flat ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\">table of contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" area-label=\"ez-toc-toggle-icon-1\"><label for=\"item-69f1d9b74c747\" aria-label=\"Table of Content\"><span style=\"display: flex;align-items: center;width: 35px;height: 30px;justify-content: center;direction:ltr;\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/label><input  type=\"checkbox\" id=\"item-69f1d9b74c747\"><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1' ><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.kolabtree.com\/blog\/ja\/cell-lines-challenges-applications\/#Conflict_Surrounding_Application_of_Cell_Lines\" title=\"\u7d30\u80de\u682a\u306e\u6d3b\u7528\u3092\u3081\u3050\u308b\u845b\u85e4\">\u7d30\u80de\u682a\u306e\u6d3b\u7528\u3092\u3081\u3050\u308b\u845b\u85e4<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.kolabtree.com\/blog\/ja\/cell-lines-challenges-applications\/#Application_of_Cell_Lines\" title=\"\u7d30\u80de\u682a\u306e\u5fdc\u7528\">\u7d30\u80de\u682a\u306e\u5fdc\u7528<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.kolabtree.com\/blog\/ja\/cell-lines-challenges-applications\/#The_Way_Forward\" title=\"\u4eca\u5f8c\u306e\u5c55\u958b\">\u4eca\u5f8c\u306e\u5c55\u958b<\/a><\/li><\/ul><\/nav><\/div>\n<p>At the base of large scale experimental <a href=\"https:\/\/www.kolabtree.com\/blog\/ja\/ensuring-reproducibility-in-ai-driven-research-how-freelance-experts-can-help-in-biotech-and-healthcare\/\">\u30ea\u30b5\u30fc\u30c1<\/a> \u3067 <a href=\"https:\/\/www.kolabtree.com\/find-an-expert\/subject\/molecular-biology?utm_source=Blog_CellLines\">\u5206\u5b50\u751f\u7269\u5b66<\/a> \u306f\u7d30\u80de\u682a\u3092\u4f7f\u7528\u3057\u3066\u3044\u307e\u3059\u3002\u4eba\u5de5\u7684\u306b\u4f5c\u6210\u3055\u308c\u3001\u7d99\u7d9a\u7684\u306b\u6210\u9577\u3057\u3001\u8a3a\u65ad\u3084\u6cbb\u7642\u306e\u767a\u898b\u306b\u5f79\u7acb\u3063\u3066\u3044\u308b\u7d30\u80de\u682a\u306f\u3001\u4eca\u3055\u3089\u7d39\u4ecb\u3059\u308b\u5fc5\u8981\u3082\u306a\u3044\u3067\u3057\u3087\u3046\u3002\u305d\u306e\u4e3b\u306a\u5206\u985e\u306f\u3001\u5f62\u614b\u7684\u7279\u5fb4\u3068\u5206\u96e2\u3057\u305f\u6839\u5143\u306e\u7d44\u7e54\u3092\u533a\u5225\u306e\u57fa\u6e96\u3068\u3057\u3066\u3044\u308b\u3002\u3057\u304b\u3057\u3001\u5927\u898f\u6a21\u306a\u7814\u7a76\u3067\u306f\u3001\u521d\u4ee3\u7d30\u80de\u3068\u305d\u308c\u3092\u7528\u3044\u3066\u958b\u767a\u3055\u308c\u305f\u7d30\u80de\u682a\u306e\u9593\u306b\u306f\u5927\u304d\u306a\u9055\u3044\u304c\u3042\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u3066\u3044\u308b\u3002\u306a\u305c\u3001\u3053\u306e\u3088\u3046\u306a\u8a66\u9a13\u7ba1\u5185\u306e\u751f\u7269\u5b66\u7684\u7d20\u6750\u304c\u7814\u7a76\u958b\u767a\u306e\u305f\u3081\u306e\u69cb\u6210\u7684\u8cc7\u6e90\u3068\u306a\u308b\u306e\u3067\u3057\u3087\u3046\u304b\uff1f\u307e\u305f\u3001\u305d\u306e\u9069\u7528\u7bc4\u56f2\u306e\u5e83\u3055\u306b\u306f\u3069\u306e\u3088\u3046\u306a\u7406\u7531\u304c\u3042\u308b\u306e\u3067\u3057\u3087\u3046\u304b\u3002\u3053\u308c\u3089\u306f\u3001\u7d30\u80de\u682a\u958b\u767a\uff08CLD\uff09\u696d\u754c\u306b\u3068\u3063\u3066\u518d\u5e30\u7684\u306a\u554f\u3044\u3067\u3042\u308b\u3002\u3053\u3053\u3067\u306f\u3001\u305d\u306e\u9069\u7528\u6027\u3092\u5408\u7406\u5316\u3057\u3001\u30dc\u30c8\u30eb\u30cd\u30c3\u30af\u3092\u8efd\u6e1b\u3059\u308b\u305f\u3081\u306b\u884c\u308f\u308c\u3066\u304d\u305f\u6539\u5584\u306b\u3064\u3044\u3066\u304a\u8a71\u3057\u307e\u3059\u3002\u7d30\u80de\u682a\u306e\u5fdc\u7528\u4f8b\u306f\u4ee5\u4e0b\u306e\u901a\u308a\u3067\u3059\u3002<\/p>\n<h3><span class=\"ez-toc-section\" id=\"Conflict_Surrounding_Application_of_Cell_Lines\"><\/span>\u7d30\u80de\u682a\u306e\u6d3b\u7528\u3092\u3081\u3050\u308b\u845b\u85e4<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u907a\u4f1d\u5b50\u578b\u3068\u8868\u73fe\u578b\u304c\u540c\u4e00\u3067\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u305f\u9023\u7d9a\u3057\u305f\u7d30\u80de\u682a\u306e\u7814\u7a76\u304c\u4f55\u5341\u5e74\u306b\u3082\u308f\u305f\u3063\u3066\u884c\u308f\u308c\u3066\u304d\u307e\u3057\u305f\u304c\u3001\u4eca\u65e5\u3001\u79d1\u5b66\u8005\u305f\u3061\u306f\u69d8\u3005\u306a\u7d30\u80de\u682a\u306e\u30ec\u30d1\u30fc\u30c8\u30ea\u30fc\u304b\u3089\u9078\u3076\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002150\u306e\u751f\u7269\u7a2e\u304b\u3089\u958b\u767a\u3055\u308c\u305f3600\u306e\u7d30\u80de\u682a\u304c\u3042\u308a\u307e\u3059\u3002\u30de\u30a6\u30b9\u306e\u30bb\u30eb\u30c8\u30ea\u7d30\u80de\u682a\uff08MSC-1\uff09\u3001Hepa1-6\u3001HeLa\u3001\u30af\u30ed\u30fc\u30f3\u7d30\u80de\u682a\u306b\u59cb\u307e\u308a\u3001CLD\u306f\u5168\u304f\u65b0\u3057\u3044\u65c5\u306b\u51fa\u3066\u3044\u307e\u3059\u3002\u73fe\u5728\u3001\u7814\u7a76\u8005\u305f\u3061\u306f\u3001\u80da\u6027\u5e79\u7d30\u80de\u3084\u81cd\u5e2f\u5e79\u7d30\u80de\u304c\u65b0\u3057\u3044CLD\u306b\u4f7f\u7528\u3055\u308c\u308b\u30ec\u30d9\u30eb\u307e\u3067\u3001\u69d8\u3005\u306a\u4eba\u5de5\u7684\u306b\u751f\u6210\u3055\u308c\u305f\u7d30\u80de\u682a\u3092\u63d0\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u4e00\u65b9\u3067\u3001\u7814\u7a76\u8005\u306f\u3001\u7d50\u679c\u306e\u7570\u5e38\u3084\u8cc7\u6e90\u306e\u6d6a\u8cbb\u306b\u3064\u306a\u304c\u308b\u305f\u3081\u3001\u7d30\u80de\u682a\u306e\u53d6\u308a\u6271\u3044\u306b\u306f\u53b3\u3057\u3044\u8ab2\u984c\u3092\u62b1\u3048\u3066\u3044\u307e\u3059\u3002 <a href=\"http:\/\/www.tandfonline.com\/doi\/abs\/10.4161\/spmg.19885\" target=\"_blank\" rel=\"noopener noreferrer\">Gurvinder Kaur et al (2012)<\/a> \u306f\u3001\u30de\u30a6\u30b9\u30bb\u30eb\u30c8\u30ea\u7d30\u80de\u304cMSC-1\u682a\u3088\u308a\u3082\u91cd\u8981\u306a\u514d\u75ab\u5b66\u7684\u7279\u6027\u3092\u6301\u3063\u3066\u3044\u308b\u3053\u3068\u3092\u793a\u3057\u305f\u3002 <a href=\"https:\/\/www.researchgate.net\/profile\/Damian_Marshall\/publication\/5775029_The_costs_of_using_unauthenticated_over-passaged_cell_lines_How_much_more_data_do_we_need\/links\/55daf2bf08aed6a199ab08dd.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Hughes et al (2007)<\/a> 18-36%\u306e\u8868\u73fe\u578b\u306e\u8cea\u304c\u3001\u8aa4\u8a8d\u3084\u30af\u30ed\u30b9\u30b3\u30f3\u30bf\u30df\u30cd\u30fc\u30b7\u30e7\u30f3\u306b\u3088\u3063\u3066\u5931\u308f\u308c\u3066\u3044\u308b\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u305f\u3002\u6700\u8fd1\u3067\u306f <a href=\"https:\/\/phys.org\/news\/2017-04-tools-optimize-cho-cell-lines.html\" target=\"_blank\" rel=\"noopener noreferrer\">\u30c1\u30e3\u30a4\u30cb\u30fc\u30ba\u30cf\u30e0\u30b9\u30bf\u30fc\u5375\u5de3\u7d30\u80de(CHO)<\/a> \u306f\u3001\u300c\u751f\u7269\u5b66\u7684\u88fd\u5264\u300d\u3068\u3057\u3066\u77e5\u3089\u308c\u308b\u4e00\u9023\u306e\u30d0\u30a4\u30aa\u533b\u85ac\u54c1\u306e\u5408\u6210\u306b\u4f7f\u7528\u3059\u308b\u3053\u3068\u304c\u307e\u3059\u307e\u3059\u56f0\u96e3\u306b\u306a\u3063\u3066\u304d\u305f\u3002\u305d\u306e\u7d50\u679c\u3001\u7d30\u80de\u682a\u304c\u9069\u7528\u3067\u304d\u306a\u3044\u7406\u7531\u3068\u3057\u3066\u3001\u7d30\u80de\u682a\u306e\u5909\u7570\u983b\u5ea6\u306e\u9ad8\u3055\u3001\u7d30\u80de\u7d99\u4ee3\u5185\u3067\u306e\u5236\u5fa1\u3055\u308c\u3066\u3044\u306a\u3044\u30af\u30ed\u30fc\u30f3\u306e\u9078\u629e\u3001\u81e8\u5e8a\u7684\u306b\u610f\u7fa9\u306e\u3042\u308b\u3082\u306e\u3078\u306e\u5909\u63db\u306e\u9650\u754c\u306a\u3069\u304c\u6319\u3052\u3089\u308c\u3066\u3044\u307e\u3059\u3002 <em>in vitro<\/em> \u30e2\u30c7\u30eb\u3092\u4f7f\u7528\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<h3><span class=\"ez-toc-section\" id=\"Application_of_Cell_Lines\"><\/span>\u7d30\u80de\u682a\u306e\u5fdc\u7528<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u3068\u306f\u3044\u3048\u3001\u7d30\u80de\u682a\u306f\u79d1\u5b66\u7814\u7a76\u3092\u884c\u3046\u4e0a\u3067\u3001\u6700\u3082\u8cbb\u7528\u5bfe\u52b9\u679c\u304c\u9ad8\u304f\u3001\u502b\u7406\u7684\u306b\u3082\u5b9f\u884c\u53ef\u80fd\u306a\u8cc7\u6e90\u3067\u3042\u308b\u3002\u7d30\u80de\u682a\u306e\u958b\u767a\u306f\u3001\u53cd\u5fa9\u7684\u306a\u7d30\u80de\u96c6\u56e3\u306b\u304a\u3051\u308b\u8868\u73fe\u578b\u3068\u907a\u4f1d\u5b50\u578b\u306e\u5747\u4e00\u6027\u3092\u7406\u60f3\u3068\u3057\u3066\u3044\u305f\u3002\u3053\u3053\u6570\u5341\u5e74\u3001\u307b\u3068\u3093\u3069\u3059\u3079\u3066\u306e\u79d1\u5b66\u7684\u958b\u767a\u304c\u7d30\u80de\u682a\u306b\u57fa\u3065\u3044\u3066\u884c\u308f\u308c\u3066\u304d\u305f\u306e\u306f\u3001\u7d30\u80de\u682a\u306e\u5b9f\u884c\u53ef\u80fd\u6027\u3068\u5bb9\u6613\u306a\u5165\u624b\u304c\u7406\u7531\u3067\u3042\u308b\u3002\u6297\u4f53\u4f5c\u88fd\u3001\u30ef\u30af\u30c1\u30f3\u958b\u767a\u3001\u85ac\u7269\u691c\u67fb\u3001\u907a\u4f1d\u5b50\u6a5f\u80fd\u7814\u7a76\u3001\u764c\u7d30\u80de\u306e\u5897\u6b96\u7814\u7a76\u3001\u4eba\u5de5\u76ae\u819a\u306e\u958b\u767a\u306a\u3069\u306b\u5229\u7528\u3055\u308c\u3066\u3044\u308b\u306e\u3082\u4e0d\u601d\u8b70\u3067\u306f\u306a\u3044\u3002<\/p>\n<p>\u764c\u3001\u76ae\u819a\u75be\u60a3\u3001\u80ba\u6a5f\u80fd\u969c\u5bb3\u306e\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u3092\u898b\u3064\u3051\u305f\u308a\u3001\u816b\u760d\u7d30\u80de\u3092\u3088\u308a\u3088\u304f\u53ef\u8996\u5316\u3059\u308b\u305f\u3081\u306b\u3001\u65b0\u3057\u3044\u7d30\u80de\u682a\u304c\u7d99\u7d9a\u7684\u306b\u958b\u767a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u7d30\u80de\u682a\u306f\u3001\u307b\u307c\u3059\u3079\u3066\u306e\u30d2\u30c8\u7d44\u7e54\u306e\u7d30\u80de\u306e\u5747\u8cea\u6027\u3092\u6a21\u5023\u3057\u3066\u304a\u308a\u3001in vitro\u30e2\u30c7\u30eb\u306e\u4f5c\u6210\u306b\u4f7f\u7528\u3055\u308c\u308b\u305f\u3081\u3001\u7d30\u80de\u682a\u306e\u8abf\u9054\u3068\u7dad\u6301\u306f\u4f9d\u7136\u3068\u3057\u3066\u5fc5\u9808\u3067\u3042\u308a\u3001CLD\u4f01\u696d\u306b\u3088\u308b\u65b0\u3057\u3044\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3084\u30d7\u30ed\u30c8\u30b3\u30eb\u304c\u6bce\u5e74\u767a\u8868\u3055\u308c\u3066\u3044\u308b\u3002Sigma Aldrich\u3001Thermo Fisher Scientific\u3001Lonza\u3001The Horizon\u306f\u3001\u7d30\u80de\u907a\u4f1d\u5b66\u7684\u30d0\u30ea\u30a2\u30f3\u30c8\u306e\u89b3\u70b9\u304b\u3089\u7d30\u80de\u682a\u3092\u7d99\u7d9a\u7684\u306b\u958b\u767a\u3057\u3001\u9032\u5316\u3055\u305b\u3066\u304d\u305f\u4f01\u696d\u3067\u3042\u308b\u3002<\/p>\n<h3><span class=\"ez-toc-section\" id=\"The_Way_Forward\"><\/span>\u4eca\u5f8c\u306e\u5c55\u958b<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u521d\u4ee3\u7d30\u80de\u682a\u3088\u308a\u3082\u7d30\u80de\u682a\u3092\u4f7f\u7528\u3057\u305f\u5834\u5408\u3001\u76f8\u53cd\u3059\u308b\u7d50\u679c\u304c\u5f97\u3089\u308c\u308b\u305f\u3081\u3001\u7814\u7a76\u8005\u306f\u3069\u3061\u3089\u306e\u7d30\u80de\u8cc7\u6e90\u3092\u4f7f\u7528\u3059\u3079\u304d\u304b\u3092\u6c7a\u5b9a\u3059\u308b\u3068\u3044\u3046\u56f0\u96e3\u306a\u8ab2\u984c\u306b\u76f4\u9762\u3057\u3066\u3044\u308b\u3002\u3053\u308c\u306b\u5bfe\u3059\u308b\u7b54\u3048\u306f <a href=\"https:\/\/www.thermofisher.com\/in\/en\/home\/life-science\/genome-editing\/genome-engineering-services\/cell-line-engineering-services.html\">\u30bb\u30eb\u30e9\u30a4\u30f3\u30a8\u30f3\u30b8\u30cb\u30a2\u30ea\u30f3\u30b0\uff08CLE\uff09\u306e\u624b\u6cd5<\/a> \u30683\u6b21\u5143\u7d30\u80de\u57f9\u990a\u306b\u57fa\u3065\u3044\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u65b0\u3057\u3044\u30a2\u30d7\u30ed\u30fc\u30c1\u306f\u3001\u30d2\u30c8\u306e\u521d\u4ee3\u7d30\u80de\u304a\u3088\u3073\/\u307e\u305f\u306f\u52d5\u7269\u306e\u7d30\u80de\u3092\u6839\u5143\u306e\u7d44\u7e54\u304b\u3089\u8abf\u9054\u3057\u3001\u9078\u629e\u7684\u306a\u57f9\u5730\u3092\u7528\u3044\u30663\u6b21\u5143\u7684\u306b\u57f9\u990a\u3057\u3001\u7d30\u80de\u304c\u30b9\u30d5\u30a7\u30ed\u30a4\u30c9\u3068\u547c\u3070\u308c\u308b\u7403\u72b6\u306e\u96c6\u5408\u4f53\u3092\u5f62\u6210\u3059\u308b\u3053\u3068\u3092\u57fa\u672c\u3068\u3057\u3066\u3044\u307e\u3059\u30023\u6b21\u5143\u7d30\u80de\u57f9\u990a\u306e\u6761\u4ef6\u3068\u3057\u3066\u306f\u3001\u9ad8\u5206\u5b50\u30de\u30c3\u30c8\u3001\u4f8b\u3048\u3070\u30dd\u30ea\u30b9\u30c1\u30ec\u30f3\u30de\u30c3\u30c8\u3001\u30dd\u30ea\u30ab\u30fc\u30dc\u30cd\u30fc\u30c8\u30d9\u30fc\u30b9\u306eECM\u7e4a\u7dad\u3001\u30b3\u30e9\u30fc\u30b2\u30f3\u30de\u30c3\u30c8\u3001\u4eba\u5de5\u7684\u306b\u4f5c\u3089\u308c\u305fin vitro\u57fa\u6750\uff08\u30b9\u30ad\u30e3\u30d5\u30a9\u30fc\u30eb\u30c9\uff09\u306a\u3069\u304c\u6319\u3052\u3089\u308c\u308b\u3002<\/p>\n<p>CLE\u306f\u3001CRISPR\u88fd\u54c1\u3092\u7528\u3044\u3066CLD\u304c\u7d30\u80de\u682a\u3092\u8a2d\u8a08\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u5148\u9032\u7684\u306a\u6280\u8853\u3067\u3059\u3002 <a href=\"https:\/\/www.thermofisher.com\/blog\/cellculture\/how-can-cell-culture-help-you\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u30b5\u30fc\u30e2\u30d5\u30a3\u30c3\u30b7\u30e3\u30fc\u30b5\u30a4\u30a8\u30f3\u30c6\u30a3\u30d5\u30a3\u30c3\u30af<\/a> \u306f\u3001\u5171\u540c\u7814\u7a76\u8005\u3067\u3042\u308b\u9867\u5ba2\u304c\u6c42\u3081\u308b\u7814\u7a76\u30d7\u30ed\u30b8\u30a7\u30af\u30c8\u306e\u8981\u4ef6\u306b\u5fdc\u3058\u3066\u3001\u65e2\u306b\u5165\u624b\u53ef\u80fd\u306a\u591a\u7a2e\u591a\u69d8\u306a\u7d30\u80de\u682a\u3092\u7528\u3044\u3066\u65b0\u3057\u3044\u7d30\u80de\u682a\u3092\u4f5c\u6210\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u304c\u3093\u7d30\u80de\u306e\u7814\u7a76\u3084\u4eba\u5de5\u81d3\u5668\u306e\u5897\u6b96\u3001\u65b0\u3057\u3044\u6cbb\u7642\u6cd5\u306a\u3069\u304c\u3001\u751f\u304d\u305f\u4eba\u9593\u306e\u7d44\u7e54\u306b\u3088\u308a\u8fd1\u3044\u3082\u306e\u3068\u306a\u308a\u3001\u30b3\u30f3\u30bf\u30df\u30cd\u30fc\u30b7\u30e7\u30f3\u3084\u5236\u5fa1\u3067\u304d\u306a\u3044\u7a81\u7136\u5909\u7570\u3092\u306a\u304f\u3059\u3053\u3068\u304c\u3067\u304d\u308b\u3002\u3053\u308c\u3089\u306f\u7d30\u80de\u682a\u306e\u5fdc\u7528\u3067\u3042\u308b\u3002<\/p>\n<p>CLE\u306b\u95a2\u3059\u308b\u5c02\u9580\u5bb6\u3078\u306e\u76f8\u8ac7\u3084\u79d1\u5b66\u8005\u3068\u306e\u5171\u540c\u7814\u7a76\u3092\u304a\u8003\u3048\u306e\u65b9\u306f\u3001\u305c\u3072\u3068\u3082 <a href=\"https:\/\/www.kolabtree.com\/find-an-expert?search=cell%20lines?utm_source=Blog_CellLines\">\u6709\u8cc7\u683c\u8005<\/a> \u3092Kolabtree\u306b\u63b2\u8f09\u3057\u307e\u3057\u305f\u3002<\/p>\n<p><em>\u672a\u6765\u3078\u3088\u3046\u3053\u305d\uff01\u300d\u3002<\/em><\/p>\n<p>&nbsp;<\/p>","protected":false},"excerpt":{"rendered":"<p>At the base of large scale experimental research in molecular biology lies the use of cell lines. Artificially generated, continuously growing and instrumental in diagnosis and treatment discoveries, cell lines don&#8217;t need further introduction. Their primary categorization considers morphological features as well as the root tissue for isolation as the basis of distinction. However, large scale research has indicated stark differences between primary cells and the cell lines developed using them. What makes these in vitro biological ingredients such constitutive resources for R&amp;D? What are the possible reasons for the gap in their applicability? These have been recursive questions for the Cell Line Development (CLD) industry. Here, we talk about<\/p>\n<div class=\"read-more\"><a href=\"https:\/\/www.kolabtree.com\/blog\/ja\/cell-lines-challenges-applications\/\" title=\"\u7d9a\u304d\u3092\u8aad\u3080\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/div>","protected":false},"author":32,"featured_media":5574,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[442,247,443,435],"tags":[444],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v20.1 (Yoast SEO v20.1) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Cell Lines - Challenges, Applications and Scope of Research<\/title>\n<meta name=\"description\" content=\"Cell are the most cost-effective and ethically viable resources for performing scientific\u00a0research. Here are the application of cell lines.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.kolabtree.com\/blog\/ja\/cell-lines-challenges-applications\/\" \/>\n<meta property=\"og:locale\" content=\"ja_JP\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Cell Lines \u2013 Challenges, Applications and Scope of Research\" \/>\n<meta property=\"og:description\" content=\"Cell are the most cost-effective and ethically viable resources for performing scientific\u00a0research. Here are the application of cell lines.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.kolabtree.com\/blog\/ja\/cell-lines-challenges-applications\/\" \/>\n<meta property=\"og:site_name\" content=\"The Kolabtree Blog\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/kolabtree\" \/>\n<meta property=\"article:published_time\" content=\"2017-09-06T06:24:23+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2020-11-09T05:05:05+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.kolabtree.com\/blog\/wp-content\/uploads\/2017\/09\/cell-lines-applications.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"640\" \/>\n\t<meta property=\"og:image:height\" content=\"426\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Mahasweta Pal\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@kolabtree\" \/>\n<meta name=\"twitter:site\" content=\"@kolabtree\" \/>\n<meta name=\"twitter:label1\" content=\"\u57f7\u7b46\u8005\" \/>\n\t<meta name=\"twitter:data1\" content=\"Mahasweta Pal\" \/>\n\t<meta name=\"twitter:label2\" content=\"\u63a8\u5b9a\u8aad\u307f\u53d6\u308a\u6642\u9593\" \/>\n\t<meta name=\"twitter:data2\" content=\"4\u5206\" \/>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Cell Lines - Challenges, Applications and Scope of Research","description":"Cell are the most cost-effective and ethically viable resources for performing scientific\u00a0research. 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She is a biotechnologist at heart with research experience in Tissue Engineering, Medical Imaging Devices and Industrial Microbiology. She majored in Biomedical Engineering from Vellore Institute of Technology and has served as an editor for journal publications from Elsevier, Wolters Kluwer Health and the Royal Society for Chemistry.","url":"https:\/\/www.kolabtree.com\/blog\/ja\/author\/mahasweta-pal\/"}]}},"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/www.kolabtree.com\/blog\/ja\/wp-json\/wp\/v2\/posts\/2396"}],"collection":[{"href":"https:\/\/www.kolabtree.com\/blog\/ja\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.kolabtree.com\/blog\/ja\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.kolabtree.com\/blog\/ja\/wp-json\/wp\/v2\/users\/32"}],"replies":[{"embeddable":true,"href":"https:\/\/www.kolabtree.com\/blog\/ja\/wp-json\/wp\/v2\/comments?post=2396"}],"version-history":[{"count":17,"href":"https:\/\/www.kolabtree.com\/blog\/ja\/wp-json\/wp\/v2\/posts\/2396\/revisions"}],"predecessor-version":[{"id":8520,"href":"https:\/\/www.kolabtree.com\/blog\/ja\/wp-json\/wp\/v2\/posts\/2396\/revisions\/8520"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.kolabtree.com\/blog\/ja\/wp-json\/wp\/v2\/media\/5574"}],"wp:attachment":[{"href":"https:\/\/www.kolabtree.com\/blog\/ja\/wp-json\/wp\/v2\/media?parent=2396"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.kolabtree.com\/blog\/ja\/wp-json\/wp\/v2\/categories?post=2396"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.kolabtree.com\/blog\/ja\/wp-json\/wp\/v2\/tags?post=2396"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}