{"id":2288,"date":"2017-07-07T12:23:36","date_gmt":"2017-07-07T12:23:36","guid":{"rendered":"https:\/\/www.kolabtree.com\/blog\/?p=2288"},"modified":"2020-02-10T14:12:18","modified_gmt":"2020-02-10T14:12:18","slug":"4-recent-advances-in-computational-biology","status":"publish","type":"post","link":"https:\/\/www.kolabtree.com\/blog\/ja\/4-recent-advances-in-computational-biology\/","title":{"rendered":"4 \u8a08\u7b97\u751f\u7269\u5b66\u306e\u6700\u8fd1\u306e\u9032\u6b69"},"content":{"rendered":"<p><em><a href=\"https:\/\/www.kolabtree.com\/find-an-expert\/subject\/computational-biology?utm_source=Blog&amp;utm_medium=Post&amp;utm_campaign=4AdvCompBio\">\u8a08\u7b97\u751f\u7269\u5b66<\/a> \u306f\u3001\u65b0\u3057\u3044\u30c6\u30af\u30ce\u30ed\u30b8\u30fc\u306e\u51fa\u73fe\u306b\u3088\u308a\u3001\u7279\u306b\u30c7\u30fc\u30bf\u306e\u53ce\u96c6\u3001\u5206\u6790\u3001\u53ef\u8996\u5316\u306e\u65b9\u6cd5\u306b\u304a\u3044\u3066\u3001\u6025\u901f\u306b\u9032\u5316\u3057\u3066\u3044\u307e\u3059\u3002\u30e9\u30b4\u30b5\u30de\u30f3\u30fb\u30a4\u30a7\u30f3\u30de\u30ea\u535a\u58eb\u304c <a href=\"https:\/\/www.kolabtree.com\/?utm_source=Blog&amp;utm_campaign=4AdvCompBio\">\u30b3\u30e9\u30d6\u30c4\u30ea\u30fc<\/a> \u30d5\u30ea\u30fc\u30e9\u30f3\u30b9\u306e\u79d1\u5b66\u8005\u304c\u30014\u3064\u306e\u6709\u671b\u306a\u9032\u6b69\u3092\u691c\u8a3c\u3057\u307e\u3059\u3002\u00a0\u00a0<\/em><\/p>\n<p>\u3092\u30d5\u30a9\u30ed\u30fc\u30a2\u30c3\u30d7\u3057\u3066\u3044\u307e\u3059\u3002 <a href=\"https:\/\/www.kolabtree.com\/blog\/computational-biology\/\">\u524d\u7d39\u4ecb\u8a18\u4e8b<\/a>\u3053\u3053\u3067\u306f\u3001\u8a08\u7b97\u751f\u7269\u5b66\u3092\u5927\u304d\u304f\u5909\u3048\u3064\u3064\u3042\u308b\u751f\u7269\u79d1\u5b66\u306e\u6700\u8fd1\u306e\u50be\u5411\u3084\u9032\u6b69\u306b\u7126\u70b9\u3092\u5f53\u3066 \u307e\u3059\u3002\u3053\u308c\u3089\u306e\u9032\u6b69\u306f\u3001\u30d3\u30c3\u30b0\u30c7\u30fc\u30bf\u89e3\u6790\u3001\u30de\u30eb\u30c1\u30b9\u30b1\u30fc\u30eb\u30e2\u30c7\u30ea\u30f3\u30b0\u306a\u3069\u3001\u8a08\u7b97\u6a5f\u30c4\u30fc\u30eb\u3084\u624b\u6cd5\u306b\u5927\u304d\u304f\u4f9d\u5b58\u3057\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u3044\u304f\u3064\u304b\u3092\u4ee5\u4e0b\u306b\u7d39\u4ecb\u3057\u307e\u3059\u3002<\/p>\n<p><strong>1.\u30d3\u30c3\u30b0\u30c7\u30fc\u30bf<\/strong><\/p>\n<p>\u3053\u308c\u306f\u30b3\u30f3\u30d4\u30e5\u30fc\u30bf\u30b5\u30a4\u30a8\u30f3\u30b9\u3067\u306f\u3088\u304f\u77e5\u3089\u308c\u305f\u7528\u8a9e\u3067\u3001\u751f\u7269\u5b66\u8005\u306b\u53d6\u308a\u4e0a\u3052\u3089\u308c\u305f\u306e\u306f\u3054\u304f\u6700\u8fd1\u306e\u3053\u3068\u3067\u3042\u308b\u3002\u6b21\u4e16\u4ee3\u30b7\u30fc\u30b1\u30f3\u30b5\u30fc\u6280\u8853\u306e\u304a\u304b\u3052\u3067\u3001\u30b2\u30ce\u30e0\u306e\u914d\u5217\u306f\u6bd4\u8f03\u7684\u77ed\u6642\u9593\u3067\u5f97\u3089\u308c\u308b\u3088\u3046\u306b\u306a\u3063\u305f\u3002\u4f8b\u3048\u3070\u3001\u30e1\u30bf\u30b2\u30ce\u30e0\u3084\u30de\u30a4\u30af\u30ed\u30d0\u30a4\u30aa\u30fc\u30e0\u306a\u3069\u306e\u30c7\u30fc\u30bf\u3092\u6271\u3046\u5834\u5408\u3001\u30c7\u30fc\u30bf\u3092\u8fc5\u901f\u306b\u751f\u6210\u3059\u308b\u3053\u3068\u306e\u610f\u7fa9\u306f\u5927\u304d\u304f\u306a\u308a\u307e\u3059\u3002\u30c7\u30fc\u30bf\u306e\u7ba1\u7406\u306f\u3069\u3046\u3059\u308c\u3070\u3044\u3044\u306e\u304b\uff1f\u9577\u671f\u9593\u306e\u4fdd\u5b58\u306f\uff1f\u3053\u306e\u3088\u3046\u306a\u81a8\u5927\u306a\u30c7\u30fc\u30bf\u3092\u89e3\u6790\u3059\u308b\u305f\u3081\u306e\u30c4\u30fc\u30eb\u306f\uff1f\u3053\u306e\u3088\u3046\u306a\u7591\u554f\u304c\u751f\u3058\u307e\u3059\u304c\u3001\u3053\u308c\u306b\u306f\u7b54\u3048\u304c\u3042\u308a\u307e\u3059\u3002\u524d\u8ff0\u306e\u3088\u3046\u306b\u3001\u3053\u308c\u306f\u751f\u7269\u5b66\u306b\u304a\u3051\u308b\u6700\u8fd1\u306e\u50be\u5411\u3067\u3059\u304c\u3001\u30b3\u30f3\u30d4\u30e5\u30fc\u30bf\u30b5\u30a4\u30a8\u30f3\u30b9\u3084\u5b9f\u9a13\u7269\u7406\u5b66\u3067\u306f\u3001\u30d3\u30c3\u30b0\u30c7\u30fc\u30bf\u306e\u53d6\u308a\u6271\u3044\u3084\u89e3\u6790\u306f\u65e5\u5e38\u7684\u306a\u4ed5\u4e8b\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"alignnone wp-image-2323\" src=\"https:\/\/www.kolabtree.com\/blog\/wp-content\/uploads\/2017\/07\/big-data-1667184_1280-1024x723.jpg\" alt=\"big-data-1667184_1280\" width=\"500\" height=\"353\" srcset=\"https:\/\/www.kolabtree.com\/blog\/wp-content\/uploads\/2017\/07\/big-data-1667184_1280-1024x723.jpg 1024w, https:\/\/www.kolabtree.com\/blog\/wp-content\/uploads\/2017\/07\/big-data-1667184_1280-300x212.jpg 300w, https:\/\/www.kolabtree.com\/blog\/wp-content\/uploads\/2017\/07\/big-data-1667184_1280-768x542.jpg 768w, https:\/\/www.kolabtree.com\/blog\/wp-content\/uploads\/2017\/07\/big-data-1667184_1280-1080x763.jpg 1080w, https:\/\/www.kolabtree.com\/blog\/wp-content\/uploads\/2017\/07\/big-data-1667184_1280.jpg 1280w, https:\/\/www.kolabtree.com\/blog\/wp-content\/uploads\/2017\/07\/big-data-1667184_1280-300x212@2x.jpg 600w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/><br \/>\nOne particular instance where <a href=\"https:\/\/www.kolabtree.com\/blog\/ja\/ensuring-reproducibility-in-ai-driven-research-how-freelance-experts-can-help-in-biotech-and-healthcare\/\">\u30ea\u30b5\u30fc\u30c1<\/a> is happening is in the file formats of biological big data. In the case of protein structure file format, the current standard is the .pdb format, a column dependent format that is parseable and both human and machine readable. However, this format fails when describing mega structures, such as the ribosome or full viral capsids. Hence, a new format has been proposed called the .pdbx format that overcomes the previous format&#8217;s limitations. There is also another format called MMTF format that spees up the loading time for structures with more then 20 million atoms within seconds.<\/p>\n<p>\u8a08\u7b97\u6a5f\u306b\u304a\u3051\u308b\u30d3\u30c3\u30b0\u30c7\u30fc\u30bf\u306b\u95a2\u3059\u308b\u305d\u306e\u4ed6\u306e\u8aad\u307f\u7269 <a href=\"https:\/\/www.kolabtree.com\/find-an-expert\/subject\/structural-biology?utm_source=Blog&amp;utm_medium=Post&amp;utm_campaign=4AdvCompBio\">\u69cb\u9020\u751f\u7269\u5b66<\/a>:<br \/>\n<a href=\"http:\/\/science.sciencemag.org\/content\/355\/6322\/248\">http:\/\/science.sciencemag.org\/content\/355\/6322\/248<br \/>\n<\/a><\/p>\n<p><strong>2.\u30af\u30e9\u30a4\u30aa\u96fb\u5b50\u9855\u5fae\u93e1\u3068XFEL\u6280\u8853<\/strong><\/p>\n<p>\u3053\u306e2\u3064\u306e\u65b9\u6cd5\u306f\u3001\u305d\u308c\u81ea\u4f53\u306f\u65b0\u3057\u3044\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u3057\u304b\u3057\u3001\u3053\u306e2\u3064\u306e\u5206\u91ce\u3067\u8d77\u304d\u3066\u3044\u308b\u73fe\u5728\u306e\u6280\u8853\u3084\u9032\u6b69\u306f\u3001\u751f\u4f53\u5206\u5b50\u69cb\u9020\u306e\u89e3\u6790\u306e\u9650\u754c\u3092\u8d85\u3048\u3064\u3064\u3042\u308a\u307e\u3059\u3002 <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3537914\/\">\u30af\u30e9\u30a4\u30aa\u96fb\u5b50\u9855\u5fae\u93e1 <\/a>\u306f\u3001\u96fb\u5b50\u9855\u5fae\u93e1\u3092\u4f7f\u3063\u3066\u751f\u4f53\u5206\u5b50\u306e3\u6b21\u5143\u69cb\u9020\u3092\u9ad8\u89e3\u50cf\u5ea6\u3067\u3068\u3089\u3048\u308b\u6280\u8853\u3067\u3042\u308b\u3002NIH\u306e\u5148\u99c6\u7684\u306a\u7814\u7a76\u5ba4\u3067\u306f\u30012.5\u00c5\u306e\u69cb\u9020\u304c\u89e3\u304b\u308c\u305f\u3053\u3068\u304c\u3042\u308b\u3002\u3053\u306e\u5206\u89e3\u80fd\u306f\u901a\u5e38\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u7d50\u6676\u69cb\u9020\u3067\u5f97\u3089\u308c\u308b\u3082\u306e\u3067\u3001X\u7dda\u30d3\u30fc\u30e0\u3092\u7167\u5c04\u3059\u308b\u6700\u9069\u306a\u7d50\u6676\u3092\u6a19\u6e96\u5316\u3059\u308b\u306e\u306b\u5c11\u306a\u304f\u3068\u30821\u301c2\u30f6\u6708\u306e\u6642\u9593\u3092\u8981\u3059\u308b\u306e\u304c\u901a\u4f8b\u3067\u3042\u308b\u3002<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"alignnone wp-image-2324\" src=\"https:\/\/www.kolabtree.com\/blog\/wp-content\/uploads\/2017\/07\/alat2-872522_1920-1024x397.jpg\" alt=\"ALAT2-872522_1920\" width=\"500\" height=\"194\" srcset=\"https:\/\/www.kolabtree.com\/blog\/wp-content\/uploads\/2017\/07\/alat2-872522_1920-1024x397.jpg 1024w, https:\/\/www.kolabtree.com\/blog\/wp-content\/uploads\/2017\/07\/alat2-872522_1920-300x116.jpg 300w, https:\/\/www.kolabtree.com\/blog\/wp-content\/uploads\/2017\/07\/alat2-872522_1920-768x298.jpg 768w, https:\/\/www.kolabtree.com\/blog\/wp-content\/uploads\/2017\/07\/alat2-872522_1920-1536x596.jpg 1536w, https:\/\/www.kolabtree.com\/blog\/wp-content\/uploads\/2017\/07\/alat2-872522_1920-1080x419.jpg 1080w, https:\/\/www.kolabtree.com\/blog\/wp-content\/uploads\/2017\/07\/alat2-872522_1920.jpg 1920w, https:\/\/www.kolabtree.com\/blog\/wp-content\/uploads\/2017\/07\/alat2-872522_1920-300x116@2x.jpg 600w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/><br \/>\n\u3053\u308c\u306b\u5bfe\u3057\u3066\u3001\u69cb\u9020\u751f\u7269\u5b66\u306b\u9769\u547d\u3092\u3082\u305f\u3089\u3059\u6700\u8fd1\u306e\u6280\u8853\u306f <a href=\"https:\/\/www.bioxfel.org\/science\/xfel\">XFEL<\/a> \u3053\u308c\u306f\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u5fae\u7d50\u6676\u306b\u9ad8\u5f37\u5ea6\u306eX\u7dda\u3092\u7167\u5c04\u3059\u308b\u65b9\u6cd5\u3067\u3059\u3002\u9ad8\u653e\u5c04\u80fd\u306e\u305f\u3081\u3001\u5fae\u5c0f\u7d50\u6676\u306f\u6587\u5b57\u901a\u308a\u713c\u304b\u308c\u3066\u30c7\u30fc\u30bf\u3092\u53d6\u5f97\u3059\u308b\u3002\u5341\u5206\u306a\u5e83\u3055\u306e\u30c7\u30fc\u30bf\u3092\u5f97\u308b\u305f\u3081\u306b\u306f\u3001\u4f55\u4e07\u500b\u3082\u306e\u5fae\u5c0f\u7d50\u6676\u304c\u5fc5\u8981\u3067\u3059\u3002\u307e\u305f\u3001\u5fae\u5c0f\u7d50\u6676\u304b\u3089\u5f97\u3089\u308c\u305f\u753b\u50cf\u306f\u3001\u4ed6\u306e\u753b\u50cf\u3068\u5408\u308f\u305b\u3066\u89e3\u6790\u3057\u3001\u751f\u4f53\u5206\u5b50\u306e\u7acb\u4f53\u69cb\u9020\u3092\u628a\u63e1\u3059\u308b\u5fc5\u8981\u304c\u3042\u308b\u3002<\/p>\n<p><span style=\"font-size: 14px;\">\u3053\u306e\u3088\u3046\u306a\u6280\u8853\u306f\u3001\u5468\u56f2\u306e\u30ce\u30a4\u30ba\u304b\u3089\u4fe1\u53f7\u3092\u8b58\u5225\u3059\u308b\u305f\u3081\u306b\u3001\u753b\u50cf\u51e6\u7406\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u3084\u3042\u308b\u7a0b\u5ea6\u306e\u6a5f\u68b0\u5b66\u7fd2\u30a2\u30d7\u30ed\u30fc\u30c1\u3092\u4f7f\u7528\u3059\u308b\u81ea\u52d5\u5316\u30bd\u30d5\u30c8\u30a6\u30a7\u30a2\u306b\u5927\u304d\u304f\u4f9d\u5b58\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306e<\/span><span style=\"font-size: 14px;\">\u00a0\u306f\u3001\u60c5\u5831\u306e\u591a\u69d8\u6027\u3068\u53d6\u5f97\u901f\u5ea6\u304c\u5929\u6587\u5b66\u7684\u3067\u3042\u308b\u305f\u3081\u3001\u30d3\u30c3\u30b0\u30c7\u30fc\u30bf\u3067\u3042\u308b\u3068\u8a00\u3048\u307e\u3059\u3002<\/span><\/p>\n<p><strong>3.\u30de\u30eb\u30c1\u30b9\u30b1\u30fc\u30eb\u30e2\u30c7\u30ea\u30f3\u30b0<\/strong><\/p>\n<p>\u5358\u4e00\u751f\u4f53\u5206\u5b50\u69cb\u9020\u306e\u30e2\u30c7\u30ea\u30f3\u30b0\u3084\u3088\u308a\u8907\u96d1\u306a\u7cfb\u3078\u306e\u5916\u633f\u3068\u306f\u7570\u306a\u308a\u3001\u30de\u30eb\u30c1\u30b9\u30b1\u30fc\u30eb\u30e2\u30c7\u30ea\u30f3\u30b0\u306f20\u4e07\u4ee5\u4e0a\u306e\u539f\u5b50\u3092\u542b\u307f\u3001\u5f97\u3089\u308c\u305f\u30c0\u30a4\u30ca\u30df\u30af\u30b9\u306f\u8907\u6570\u306e\u6210\u5206\uff08\u540c\u7a2e\u307e\u305f\u306f\u7570\u7a2e\uff09\u306e\u9577\u3044\u6642\u9593\u7bc4\u56f2\u306e\u76f8\u4e92\u4f5c\u7528\u3068\u8907\u96d1\u306a\u6319\u52d5\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u5b9f\u9a13\u304b\u3089\u751f\u6210\u3055\u308c\u308b\u30c7\u30fc\u30bf\u306f\u3001\u5f97\u3089\u308c\u308b\u30c7\u30fc\u30bf\u30dd\u30a4\u30f3\u30c8\u306e\u6570\u3001\u307e\u305f\u7d71\u8a08\u7684\u306a\u6709\u610f\u6027\u3092\u5f97\u308b\u305f\u3081\u306e\u8907\u6570\u56de\u306e\u5b9f\u884c\u306b\u3088\u308a\u3001\u81a8\u5927\u306a\u91cf\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n<p>\u30de\u30eb\u30c1\u30b9\u30b1\u30fc\u30eb\u30e2\u30c7\u30ea\u30f3\u30b0\u304c\u4f7f\u308f\u308c\u305f\u4f8b\u3068\u3057\u3066\u3001\u30bb\u30eb\u30ed\u30fc\u30b9\u306b\u4ed8\u7740\u3059\u308b\u7570\u7a2e\u30bf\u30f3\u30d1\u30af\u8cea\u3068\u9175\u7d20\u304b\u3089\u306a\u308b\u30d0\u30af\u30c6\u30ea\u30a2\u306e\u8907\u5408\u69cb\u9020\u4f53\u3067\u3042\u308b\u30bb\u30eb\u30ed\u30bd\u30fc\u30e0\u306e\u30c0\u30a4\u30a2\u30cb\u30ba\u30e0\u3092\u7406\u89e3\u3059\u308b\u3053\u3068\u304c\u6319\u3052\u3089\u308c\u307e\u3059\u3002\u30bb\u30eb\u30ed\u30bd\u30fc\u30e0\u306f\u3001\u30d0\u30a4\u30aa\u71c3\u6599\u306e\u5206\u91ce\u3001\u7279\u306b\u30d0\u30a4\u30aa\u30a8\u30bf\u30ce\u30fc\u30eb\u751f\u7523\u306b\u304a\u3044\u3066\u5de5\u696d\u7684\u306b\u91cd\u8981\u3067\u3042\u308b\u3002<\/p>\n<p>\u3055\u3089\u306b\u8aad\u3080\u00a0<a href=\"http:\/\/www.ks.uiuc.edu\/Research\/biofuels\/\">http:\/\/www.ks.uiuc.edu\/Research\/biofuels\/<\/a><\/p>\n<p><strong>4.\u30b7\u30f3\u30b0\u30eb\u30bb\u30eb\u30b7\u30fc\u30b1\u30f3\u30b9<\/strong><\/p>\n<p>\u8907\u6570\u306e\u7d30\u80de\u3092\u898b\u308b\u306e\u3067\u306f\u306a\u304f\u3001\u500b\u3005\u306e\u7d30\u80de\u3092\u5206\u96e2\u3057\u3066RNA\u3092\u62bd\u51fa\u3057\u3001\u305d\u306e\u914d\u5217\u3092\u6c7a\u5b9a\u3059\u308b\u306e\u304c\u6700\u65b0\u306e\u6280\u8853\u3067\u3059\u3002\u3053\u306e\u6700\u65b0\u306e\u6280\u8853\u306f\u3001\u6b21\u306e\u3088\u3046\u306b\u547c\u3070\u308c\u3066\u3044\u307e\u3059\u3002 <a href=\"http:\/\/www.nature.com\/news\/single-cell-sequencing-made-simple-1.22233\">\u30b7\u30f3\u30b0\u30eb\u30bb\u30ebRNA\u30b7\u30fc\u30b1\u30f3\u30b7\u30f3\u30b0\u307e\u305f\u306fscRNA-seq<\/a>.\u3053\u306eNature\u306e\u8ad6\u6587\u3067\u306f\u3001\u3053\u306e\u65b9\u6cd5\u3068\u305d\u306e\u5229\u70b9\u306b\u3064\u3044\u3066\u3001\u6b21\u306e\u3088\u3046\u306b\u8a00\u53ca\u3057\u3066\u3044\u308b\u3002<\/p>\n<blockquote><p>\u500b\u3005\u306e\u7d30\u80de\u3092\u64cd\u4f5c\u3059\u308b\u306e\u306f\u5927\u304d\u306a\u96c6\u56e3\u3088\u308a\u3082\u306f\u308b\u304b\u306b\u96e3\u3057\u304f\u3001\u307e\u305f\u3001\u305d\u308c\u305e\u308c\u306e\u7d30\u80de\u304b\u3089\u5f97\u3089\u308c\u308bRNA\u306f\u3054\u304f\u308f\u305a\u304b\u3067\u3042\u308b\u305f\u3081\u3001\u5931\u6557\u306f\u8a31\u3055\u308c\u306a\u3044\u306e\u3060\u3002\u307e\u305f\u3001\u81a8\u5927\u306a\u91cf\u306e\u30c7\u30fc\u30bf\u3092\u5206\u6790\u3059\u308b\u3053\u3068\u3082\u554f\u984c\u3067\u3059\u3002\u7279\u306b\u3001\u4f7f\u7528\u3059\u308b\u30c4\u30fc\u30eb\u304c\u76f4\u611f\u7684\u3067\u306a\u3044\u3053\u3068\u304c\u539f\u56e0\u3067\u3059\u3002<\/p><\/blockquote>\n<p>scRNA-seq\u306e\u30ef\u30fc\u30af\u30d5\u30ed\u30fc\u3068\u30c4\u30fc\u30eb\u306b\u95a2\u3059\u308b\u512a\u308c\u305f\u30ec\u30d3\u30e5\u30fc\u304c\u3053\u3053\u306b\u63b2\u8f09\u3055\u308c\u3066\u3044\u307e\u3059\u3002 <a href=\"https:\/\/doi.org\/10.3389\/fgene.2016.00163\">h<span style=\"font-size: 14px;\">ttps:\/\/doi.org\/10.3389\/fgene.2016.00163<\/span><\/a><\/p>\n<hr \/>\n<p><b>\u304b\u3089\u306e\u76f8\u8ac7\u306b\u4e57\u3063\u3066\u307b\u3057\u3044\u3002 <a href=\"https:\/\/www.kolabtree.com\/find-an-expert\/subject\/computational-biology?utm_source=Blog&amp;utm_medium=Post&amp;utm_campaign=4AdvCompBio\">\u8a08\u7b97\u6a5f\u751f\u7269\u5b66\u8005<\/a>?\u3092\u96c7\u3046\u3002 <a href=\"https:\/\/www.kolabtree.com\/find-an-expert\/subject\/computational-biology?utm_source=Blog&amp;utm_medium=Post&amp;utm_campaign=4AdvCompBio\">\u30d5\u30ea\u30fc\u30e9\u30f3\u30b9\u30fb\u30b3\u30f3\u30d4\u30e5\u30fc\u30bf\u30fc\u30fb\u30d0\u30a4\u30aa\u30ed\u30b8\u30fc<\/a> \u30a8\u30ad\u30b9\u30d1\u30fc\u30c8<\/b><b>\u00a0\u3092Kolabtree\u306b\u63b2\u8f09\u3057\u307e\u3057\u305f\u3002\u30d7\u30ed\u30b8\u30a7\u30af\u30c8\u3092\u6295\u7a3f\u3057\u3066\u3001\u898b\u7a4d\u3082\u308a\u3092\u3082\u3089\u3046\u306e\u306f\u7121\u6599\u3067\u3059\u3002<\/b><\/p>\n<p>Yennamalli\u535a\u58eb\u306b\u30d7\u30ed\u30b8\u30a7\u30af\u30c8\u306e\u76f8\u8ac7\u3092\u3057\u305f\u3044\u3067\u3059\u304b\uff1fKolabtree\u3067\u5f7c\u3068\u9023\u7d61\u3092\u53d6\u3063\u3066\u304f\u3060\u3055\u3044\u3002 <a href=\"https:\/\/www.kolabtree.com\/find-an-expert\/ragothaman-yennamalli\/?utm_source=Blog&amp;utm_campaign=4AdvCompBio\">\u3053\u308c<\/a>.<\/p>\n<p>\u95a2\u9023\u3059\u308b\u5c02\u9580\u5bb6<br \/>\n<a href=\"https:\/\/www.kolabtree.com\/find-an-expert\/subject\/Bioinformatics?utm_source=Blog&amp;utm_medium=Post&amp;utm_campaign=4AdvCompBio\">\u30d0\u30a4\u30aa\u30a4\u30f3\u30d5\u30a9\u30de\u30c6\u30a3\u30b7\u30e3\u30f3\u306e\u63a1\u7528<\/a>\u00a0 \u00a0 \u00a0 \u00a0 \u00a0<a href=\"https:\/\/www.kolabtree.com\/find-an-expert\/subject\/Molecular-Biology?utm_source=Blog&amp;utm_medium=Post&amp;utm_campaign=4AdvCompBio\">\u5206\u5b50\u751f\u7269\u5b66\u8005\u306e\u63a1\u7528\u00a0<\/a> \u00a0 \u00a0 <a href=\"https:\/\/www.kolabtree.com\/find-an-expert\/subject\/biostatistics?utm_source=Blog&amp;utm_medium=Post&amp;utm_campaign=4AdvCompBio\">\u30d0\u30a4\u30aa\u30b9\u30bf\u30c6\u30a3\u30b7\u30e3\u30f3\u306e\u63a1\u7528<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>Computational biology is rapidly evolving with the advent of new technologies, especially in the way we collect, analyze and visualize data. Dr. Ragothaman Yennmalli, a Kolabtree freelancer and scientist, examines four promising advances.\u00a0\u00a0 Following up on the previous introductory post, here I will highlight some of the recent trends or recent advances in the biological sciences that are transforming computational biology. These advances rely heavily on computational tools and methods &#8212; big data analysis, multiscale modelling, etc. Some of them are listed below. 1. Big Data This is a well known term in computer science and has been picked by biologists only recently. Thanks to the next generation sequencing techniques,<\/p>\n<div class=\"read-more\"><a href=\"https:\/\/www.kolabtree.com\/blog\/ja\/4-recent-advances-in-computational-biology\/\" title=\"\u7d9a\u304d\u3092\u8aad\u3080\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/div>","protected":false},"author":26,"featured_media":2324,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[442,398,247,435],"tags":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v20.1 (Yoast SEO v20.1) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Computational biology: 4 recent advances - Kolabtree Blog<\/title>\n<meta name=\"description\" content=\"Recent advances in computational biology that are changing the way we look at genomic data, structural biology and RNA sequencing.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.kolabtree.com\/blog\/ja\/4-recent-advances-in-computational-biology\/\" \/>\n<meta property=\"og:locale\" content=\"ja_JP\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"4 Recent Advances in Computational Biology\" \/>\n<meta property=\"og:description\" content=\"Recent advances in computational biology that are changing the way we look at genomic data, structural biology and RNA sequencing.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.kolabtree.com\/blog\/ja\/4-recent-advances-in-computational-biology\/\" \/>\n<meta property=\"og:site_name\" content=\"The Kolabtree Blog\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/kolabtree\" \/>\n<meta property=\"article:published_time\" content=\"2017-07-07T12:23:36+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2020-02-10T14:12:18+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.kolabtree.com\/blog\/wp-content\/uploads\/2017\/07\/alat2-872522_1920.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1920\" \/>\n\t<meta property=\"og:image:height\" content=\"745\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Ragothaman Yennamalli\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@kolabtree\" \/>\n<meta name=\"twitter:site\" content=\"@kolabtree\" \/>\n<meta name=\"twitter:label1\" content=\"\u57f7\u7b46\u8005\" \/>\n\t<meta name=\"twitter:data1\" content=\"Ragothaman Yennamalli\" \/>\n\t<meta name=\"twitter:label2\" content=\"\u63a8\u5b9a\u8aad\u307f\u53d6\u308a\u6642\u9593\" \/>\n\t<meta name=\"twitter:data2\" content=\"4\u5206\" \/>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Computational biology: 4 recent advances - 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He conducted postdoctoral research at Iowa State University (2009-2011), University of Wisconsin-Madison (2011-2012), and Rice University (2012-2014). Currently he is an Assistant Professor at Jaypee University of Information Technology, Waknaghat, Himachal Pradesh, India.","url":"https:\/\/www.kolabtree.com\/blog\/ja\/author\/ragothaman\/"}]}},"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/www.kolabtree.com\/blog\/ja\/wp-json\/wp\/v2\/posts\/2288"}],"collection":[{"href":"https:\/\/www.kolabtree.com\/blog\/ja\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.kolabtree.com\/blog\/ja\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.kolabtree.com\/blog\/ja\/wp-json\/wp\/v2\/users\/26"}],"replies":[{"embeddable":true,"href":"https:\/\/www.kolabtree.com\/blog\/ja\/wp-json\/wp\/v2\/comments?post=2288"}],"version-history":[{"count":19,"href":"https:\/\/www.kolabtree.com\/blog\/ja\/wp-json\/wp\/v2\/posts\/2288\/revisions"}],"predecessor-version":[{"id":6896,"href":"https:\/\/www.kolabtree.com\/blog\/ja\/wp-json\/wp\/v2\/posts\/2288\/revisions\/6896"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.kolabtree.com\/blog\/ja\/wp-json\/wp\/v2\/media\/2324"}],"wp:attachment":[{"href":"https:\/\/www.kolabtree.com\/blog\/ja\/wp-json\/wp\/v2\/media?parent=2288"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.kolabtree.com\/blog\/ja\/wp-json\/wp\/v2\/categories?post=2288"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.kolabtree.com\/blog\/ja\/wp-json\/wp\/v2\/tags?post=2288"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}