{"id":7723,"date":"2020-06-01T13:28:13","date_gmt":"2020-06-01T13:28:13","guid":{"rendered":"https:\/\/www.kolabtree.com\/blog\/?p=7723"},"modified":"2020-06-01T13:39:27","modified_gmt":"2020-06-01T13:39:27","slug":"covid-19-and-maternal-health-is-the-virus-a-threat","status":"publish","type":"post","link":"https:\/\/www.kolabtree.com\/blog\/fr\/covid-19-and-maternal-health-is-the-virus-a-threat\/","title":{"rendered":"COVID-19 et la sant\u00e9 maternelle : le virus est-il une menace ?"},"content":{"rendered":"

Laura Moro<\/a>chercheur biom\u00e9dical exp\u00e9riment\u00e9 et r\u00e9dacteur scientifique<\/a>Le rapport de la Commission europ\u00e9enne sur la grossesse et la sant\u00e9 maternelle (COVID-19) traite de l'effet du COVID-19 sur la grossesse et la sant\u00e9 maternelle.\u00a0<\/em><\/p>\n

La maladie \u00e0 coronavirus 2019 (COVID-19), caus\u00e9e par le coronavirus 2 du syndrome respiratoire aigu s\u00e9v\u00e8re (SRAS-CoV-2), continue de prendre de l'ampleur dans le monde entier, l'Europe et les \u00c9tats-Unis \u00e9tant d\u00e9sormais les \u00e9picentres de la pand\u00e9mie. Au 15 avril, on compte pr\u00e8s de deux millions de cas d\u00e9clar\u00e9s et plus de 123 000 d\u00e9c\u00e8s dans le monde, de nombreux pays connaissant une transmission communautaire (1). <\/span>Bien que la majorit\u00e9 des infections par le SRAS-CoV-2 soient b\u00e9nignes, les personnes \u00e2g\u00e9es et les personnes souffrant de comorbidit\u00e9s - notamment de maladies cardiovasculaires et respiratoires, d'hypertension, de diab\u00e8te et de cancer - courent un risque accru de maladie grave et de d\u00e9c\u00e8s (2,3).\u00a0<\/span><\/p>\n

Les femmes enceintes sont particuli\u00e8rement vuln\u00e9rables \u00e0 plusieurs maladies infectieuses qui peuvent entra\u00eener des cons\u00e9quences n\u00e9fastes pour la m\u00e8re et le f\u0153tus (4-6). Les adaptations immunologiques et physiologiques qui se produisent pendant la gestation sont \u00e0 l'origine de ce risque accru (7). Lors des pr\u00e9c\u00e9dentes \u00e9pid\u00e9mies caus\u00e9es par le SRAS-CoV et le CoV du syndrome respiratoire du Moyen-Orient (MERS-CoV), plusieurs femmes enceintes ont contract\u00e9 l'infection. Le SRAS-CoV - un \" cousin \" du SRAS-CoV-2 - a \u00e9t\u00e9 associ\u00e9 \u00e0 une maladie maternelle grave, \u00e0 la mort de la m\u00e8re, \u00e0 un avortement spontan\u00e9, \u00e0 un retard de croissance intra-ut\u00e9rin grave, \u00e0 un accouchement pr\u00e9matur\u00e9 et \u00e0 des complications gastro-intestinales potentiellement mortelles chez le nouveau-n\u00e9 (8). Parmi les quelques cas connus de femmes enceintes infect\u00e9es par le MERS-CoV, plusieurs d\u00e9c\u00e8s maternels et n\u00e9onatals et des mortinaissances ont \u00e9t\u00e9 signal\u00e9s (9).<\/span><\/p>\n

Les communaut\u00e9s scientifique et m\u00e9dicale d\u00e9ploient d'immenses efforts pour partager les informations sur le COVID-19. Il existe actuellement plus de 20 rapports de cas et s\u00e9ries de cas publi\u00e9s pr\u00e9sentant des femmes enceintes infect\u00e9es par le SRAS-CoV-2 et quelques \u00e9tudes cas-t\u00e9moins, dont la majorit\u00e9 provient de Chine. Les femmes enceintes semblent pr\u00e9senter une maladie similaire \u00e0 celle de leurs homologues non enceintes, la fi\u00e8vre et la toux \u00e9tant les sympt\u00f4mes les plus fr\u00e9quents (10). Il n'existe aucune preuve de transmission verticale du virus de la m\u00e8re infect\u00e9e au f\u0153tus (11), bien que quelques nouveau-n\u00e9s aient \u00e9t\u00e9 test\u00e9s positifs quelques heures apr\u00e8s la naissance (12,13). Plusieurs effets ind\u00e9sirables pour la m\u00e8re et le f\u0153tus ont \u00e9t\u00e9 signal\u00e9s, notamment l'accouchement pr\u00e9matur\u00e9, la d\u00e9tresse f\u0153tale, le faible poids de naissance et les sympt\u00f4mes respiratoires chez le nouveau-n\u00e9 (10,14). L'accouchement pr\u00e9matur\u00e9, principale cause de d\u00e9c\u00e8s chez les enfants de moins de cinq ans, appara\u00eet comme l'issue d\u00e9favorable la plus fr\u00e9quente de la grossesse caus\u00e9e par les coronavirus (15). Il convient donc de prendre en compte les futures m\u00e8res dans les strat\u00e9gies de pr\u00e9vention et de traitement contre le COVID-19, en veillant \u00e0 la s\u00e9curit\u00e9 des m\u00e9dicaments et des vaccins pendant la grossesse.<\/span><\/p>\n

Les femmes enceintes et les nouveau-n\u00e9s vivant dans des environnements \u00e0 faibles ressources, ainsi que les r\u00e9fugi\u00e9s et les personnes vivant dans des zones de conflit, constituent l'une des populations les plus vuln\u00e9rables, et des efforts concert\u00e9s sont n\u00e9cessaires de toute urgence pour garantir leur sant\u00e9 et leur bien-\u00eatre. La prestation des services de sant\u00e9 - y compris, par exemple, la chimiopr\u00e9vention du paludisme pour les femmes enceintes - devrait \u00eatre garantie pendant la pand\u00e9mie, en \u00e9vitant l'effet perturbateur des \u00e9pid\u00e9mies pr\u00e9c\u00e9dentes (16).\u00a0<\/span><\/p><\/blockquote>\n

Le site OMS<\/a>ainsi que d'autres organisations internationales et autorit\u00e9s sanitaires nationales, ont publi\u00e9 des recommandations provisoires concernant les soins et la prise en charge des femmes enceintes infect\u00e9es par le SRAS-CoV-2 (17). Ces recommandations d\u00e9conseillent les accouchements par c\u00e9sarienne inutiles et encouragent l'allaitement maternel si possible. <\/span>Bien que nous disposions encore de peu de donn\u00e9es sur l'impact du COVID-19 sur les femmes enceintes et les nouveau-n\u00e9s, <\/span>d\u00e9pistage syst\u00e9matique et suivi attentif de toute suspicion d'infection par le SRAS-CoV-2 <\/span>pendant la grossesse<\/span> est crucial pour garantir la sant\u00e9 maternelle.<\/span><\/p>\n

A propos de l'auteur<\/strong>\"\"<\/a><\/p>\n

Laura Moro, PhD, is a researcher and science & health writer. She is particularly interested in infectious diseases, global and planetary health. She conducted recherche<\/a> for several years on infectious diseases affecting pregnant women in Sub-Saharan Africa.\u00a0<\/span>ENGAGER LAURA<\/a><\/p><\/blockquote>\n

Vous avez besoin de consulter un expert en coronavirus ? Parlez avec Les chercheurs de COVID-19<\/a> directement sur Kolabtree. Louez r\u00e9dacteurs scientifiques<\/a> pour une aide \u00e0 la v\u00e9rification des informations et \u00e0 la r\u00e9daction scientifique. Contactez experts en mati\u00e8re de grossesse<\/a> et l'accouchement.\u00a0 Commencez maintenant<\/a><\/strong><\/p>\n

R\u00e9f\u00e9rences<\/b><\/p>\n

    \n
  1. Organisation mondiale de la sant\u00e9. Rapport de situation sur la maladie \u00e0 coronavirus 2019 (COVID-19) - 86 (15 avril).\u00a0<\/span><\/li>\n
  2. Yang J, Zheng Y, Gou X, Pu K, Chen Z, Guo Q, et al. Prevalence of comorbidities in the novel Wuhan coronavirus (COVID-19) infection : a systematic review and meta-analysis. Int J Infect Dis. 2020 Mar 12.\u00a0<\/span><\/li>\n
  3. Wu Z, McGoogan JM. Caract\u00e9ristiques et le\u00e7ons importantes de l'\u00e9pid\u00e9mie de coronavirus 2019 (COVID-19) en Chine. JAMA. 24 f\u00e9vrier 2020.\u00a0<\/span><\/li>\n
  4. Thompson JM, Eick SM, Dailey C, Dale AP, Mehta M, Nair A, et al. Relation entre le paludisme associ\u00e9 \u00e0 la grossesse et les r\u00e9sultats d\u00e9favorables de la grossesse : une revue syst\u00e9matique et une m\u00e9ta-analyse. J Trop Pediatr. 2019 Oct 10.\u00a0<\/span><\/li>\n
  5. Shi T, Huang L-J, Xiong Y-Q, Zhong Y-Y, Yang J-J, Fu T, et al. The risk of herpes simplex virus and human cytomegalovirus infection during pregnancy upon adverse pregnancy outcomes : A meta-analysis. J Clin Virol. 2018 Jul;104:48-55.\u00a0<\/span><\/li>\n
  6. Mertz D, Geraci J, Winkup J, Gessner BD, Ortiz JR, Loeb M. Pregnancy as a risk factor for severe outcomes from influenza virus infection : A systematic review and meta-analysis of observational studies. Vaccine. 2017 Jan 23;35(4):521-8.\u00a0<\/span><\/li>\n
  7. Kourtis AP, Read JS, Jamieson DJ. Pregnancy and Infection. N Engl J Med. Soci\u00e9t\u00e9 m\u00e9dicale du Massachusetts ; 2014 Jun 5;370(23):2211-8.\u00a0<\/span><\/li>\n
  8. Wong SF, Chow KM, Leung TN, Ng WF, Ng TK, Shek CC, et al. Pregnancy and perinatal outcomes of women with severe acute respiratory syndrome. Am J Obstet Gynecol. 2004 Jul;191(1):292-7.\u00a0<\/span><\/li>\n
  9. Alfaraj SH, Al-Tawfiq JA, Memish ZA. Infection par le coronavirus du syndrome respiratoire du Moyen-Orient (MERS-CoV) pendant la grossesse : Report of two cases and review of the literature. J Microbiol Immunol Infect. 2019 Jun;52(3):501-3.\u00a0<\/span><\/li>\n
  10. Zaigham M, Andersson O. Maternal and Perinatal Outcomes with COVID-19 : a systematic review of 108 pregnancies. Acta Obstet Gynecol Scand. 2020 Apr 7.<\/span><\/li>\n
  11. Karimi-Zarchi M, Neamatzadeh H, Dastgheib SA, Abbasi H, Mirjalili SR, Behforouz A, et al. Vertical Transmission of Coronavirus Disease 19 (COVID-19) from Infected Pregnant Mothers to Neonates : A Review. Fetal Pediatr Pathol. 2020 Apr 2;1-5.\u00a0<\/span><\/li>\n
  12. Zeng L, Xia S, Yuan W, Yan K, Xiao F, Shao J, et al. Neonatal Early-Onset Infection with SARS-CoV-2 in 33 Neonates Born to Mothers With COVID-19 in Wuhan, China. JAMA Pediatr. 2020 Mar 26.\u00a0<\/span><\/li>\n
  13. Dong L, Tian J, He S, Zhu C, Wang J, Liu C, et al. Possible Vertical Transmission of SARS-CoV-2 From an Infected Mother to Her Newborn. JAMA. 2020 Mar 26.\u00a0<\/span><\/li>\n
  14. Li N, Han L, Peng M, Lv Y, Ouyang Y, Liu K, et al. Maternal and neonatal outcomes of pregnant women with COVID-19 pneumonia : a case-control study. Clin Infect Dis. 2020 Mar 30.\u00a0<\/span><\/li>\n
  15. Di Mascio D, Khalil A, Saccone G, Rizzo G, Buca D, Liberati M, et al. Outcome of Coronavirus spectrum infections (SARS, MERS, COVID 1 -19) during pregnancy : a systematic review and meta-analysis. Am J Obstet Gynecol MFM. 2020 Mar 25;100107.\u00a0<\/span><\/li>\n
  16. Organisation mondiale de la sant\u00e9. L'OMS exhorte les pays \u00e0 assurer la continuit\u00e9 des services antipaludiques dans le contexte de la pand\u00e9mie de COVID-19 [Internet]. [cit\u00e9 en 2020 le 2 avril]. Disponible sur : https:\/\/www.who.int\/news-room\/detail\/25-03-2020-who-urges-countries-to-ensure-the-continuity-of-malaria-services-in-the-context-of-the-covid-19-pandemic<\/span><\/li>\n
  17. Organisation mondiale de la sant\u00e9. Prise en charge clinique de l'infection respiratoire aigu\u00eb s\u00e9v\u00e8re en cas de suspicion de COVID-19. Directives provisoires. 2020.\u00a0<\/span><\/li>\n<\/ol>\n

     <\/p>","protected":false},"excerpt":{"rendered":"

    Laura Moro, chercheuse biom\u00e9dicale exp\u00e9riment\u00e9e et r\u00e9dactrice scientifique, \u00e9voque l'effet du COVID-19 sur la grossesse et la sant\u00e9 maternelle. La maladie \u00e0 coronavirus 2019 (COVID-19), caus\u00e9e par le coronavirus 2 du syndrome respiratoire aigu s\u00e9v\u00e8re (SRAS-CoV-2), continue de progresser dans le monde entier, l'Europe et les \u00c9tats-Unis \u00e9tant d\u00e9sormais les \u00e9picentres de la pand\u00e9mie. Au 15 avril, pr\u00e8s de deux millions de personnes ont \u00e9t\u00e9 infect\u00e9es par le SRAS-CoV-2.<\/p>\n

    Lire la suite<\/a><\/div>","protected":false},"author":12,"featured_media":7726,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[558,443],"tags":[],"acf":[],"yoast_head":"\nCOVID-19 and maternal health: is the virus a threat? - The Kolabtree Blog<\/title>\n<meta name=\"description\" content=\"How does COVID-19 affect pregnant women and maternal health? 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