{"id":4989,"date":"2018-11-21T12:19:49","date_gmt":"2018-11-21T12:19:49","guid":{"rendered":"https:\/\/blog.kolabtree.com\/?p=4989"},"modified":"2018-11-22T12:09:46","modified_gmt":"2018-11-22T12:09:46","slug":"15-ways-to-reduce-sample-size-in-clinical-trials-infographic","status":"publish","type":"post","link":"https:\/\/www.kolabtree.com\/blog\/fr\/15-ways-to-reduce-sample-size-in-clinical-trials-infographic\/","title":{"rendered":"[INFOGRAPHIE] 15 fa\u00e7ons de r\u00e9duire la taille de l'\u00e9chantillon dans les essais cliniques"},"content":{"rendered":"

Les co\u00fbts des essais cliniques ont explos\u00e9 au cours de la derni\u00e8re d\u00e9cennie, des rapports r\u00e9cents indiquant qu'entre 2008 et 2013, le co\u00fbt moyen par patient a augment\u00e9 de $23 600. L'un des principaux facteurs contribuant au co\u00fbt d'un essai clinique<\/a> est le recrutement des sujets et les co\u00fbts de personnel associ\u00e9s.\u00a0<\/span>Ainsi, l'examen de toutes les possibilit\u00e9s de r\u00e9duire la taille de l'\u00e9chantillon d'une \u00e9tude est une \u00e9tape importante et n\u00e9cessaire dans le d\u00e9veloppement d'un m\u00e9dicament.<\/span>
\n<\/span><\/p>\n

La r\u00e9duction de la taille de l'\u00e9chantillon sans perte de puissance peut \u00eatre r\u00e9alis\u00e9e selon l'un des trois principes suivants.<\/span><\/p>\n

Dans cette infographie, nous les examinons et pr\u00e9sentons 15 fa\u00e7ons dont les chercheurs peuvent r\u00e9duire la taille des \u00e9chantillons dans les essais cliniques.<\/span><\/p>\n

\"\"<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
15 fa\u00e7ons de r\u00e9duire la taille de l'\u00e9chantillon dans les essais cliniques<\/b><\/td>\n<\/tr>\n
#<\/b><\/td>\nM\u00e9thode<\/b><\/td>\nPotentiel\u00a0<\/b>R\u00e9duction<\/b><\/td>\n<\/tr>\n
1<\/span><\/td>\nAjustement pour les variables ind\u00e9pendantes dans l'analyse finale<\/span><\/td>\n0 – 10%<\/span><\/td>\n<\/tr>\n
2<\/span><\/td>\nStratifier les patients<\/span><\/td>\n0 - 20%<\/span><\/td>\n<\/tr>\n
3<\/span><\/td>\nEnrichir les patients<\/span><\/td>\n0 - 20%<\/span><\/td>\n<\/tr>\n
4<\/span><\/td>\nUtiliser une r\u00e9ponse soutenue<\/span><\/td>\n0 - 25%<\/span><\/td>\n<\/tr>\n
5<\/span><\/td>\nUtiliser des comparaisons par paires<\/span><\/td>\n0 - 30%<\/span><\/td>\n<\/tr>\n
6<\/span><\/td>\nAnalyse de la fr\u00e9quence d'utilisation<\/span><\/td>\n0 - 40%<\/span><\/td>\n<\/tr>\n
7<\/span><\/td>\nUtiliser une technique statistique qui correspond \u00e0 la courbe de r\u00e9ponse anticip\u00e9e<\/span><\/td>\n0 - 50%<\/span><\/td>\n<\/tr>\n
8<\/span><\/td>\nUtiliser des crit\u00e8res de substitution<\/span><\/td>\n0 - 70%<\/span><\/td>\n<\/tr>\n
9<\/span><\/td>\nAugmenter le taux de l'\u00e9v\u00e9nement<\/span><\/td>\n0 – 90%<\/span><\/td>\n<\/tr>\n
10<\/span><\/td>\nMener un essai clinique rigoureux<\/span><\/td>\n5 – 20%<\/span><\/td>\n<\/tr>\n
11<\/span><\/td>\nUtiliser le seuil optimal pour le point final binaire<\/span><\/td>\n10 - 30%<\/span><\/td>\n<\/tr>\n
12<\/span><\/td>\nUtiliser une variable continue<\/span><\/td>\n10 - 40%<\/span><\/td>\n<\/tr>\n
13<\/span><\/td>\nUtiliser la conception adaptative<\/span><\/td>\n10 - 50%<\/span><\/td>\n<\/tr>\n
14<\/span><\/td>\nUtiliser des \u00e9tudes crois\u00e9es<\/span><\/td>\n50 - 70%<\/span><\/td>\n<\/tr>\n
15<\/span><\/td>\nUtiliser les plans factoriels<\/span><\/td>\n50 - 75%<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

Jetez un coup d'\u0153il au guide d\u00e9taill\u00e9 sur le <\/span>nQuery Taille de l'\u00e9chantillon Site web du logiciel<\/span><\/a>.<\/span><\/p>\n

Vous avez besoin d'aide pour concevoir un essai clinique ? Engager des experts qualifi\u00e9s<\/a> sur Kolabtree qui peuvent vous aider avec les m\u00e9thodes de collecte de donn\u00e9es, l'analyse et la validation statistique, et l'optimisation de la conception de l'\u00e9tude. C'est gratuit de poster votre projet et d'obtenir des devis.
\n<\/b><\/p>\n

 <\/p>","protected":false},"excerpt":{"rendered":"

Clinical trial costs have surged over the past decade, with recent reports stating that from 2008 to 2013, the average cost per patient increased by $23,600. A major contributor to the cost of a clinical trial is subject recruitment and the associated staff costs.\u00a0So, examining every opportunity to reduce the sample size for a study<\/p>\n

Lire la suite<\/a><\/div>","protected":false},"author":75,"featured_media":5048,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[443,435],"tags":[467,464,459,454,463,458,455,462],"acf":[],"yoast_head":"\n[INFOGRAPHIC] 15 Ways to Reduce Sample Size In Clinical Trials - The Kolabtree Blog<\/title>\n<meta name=\"description\" content=\"In this infographic we examine 15 ways and oppportunities for researchers to reduce sample size in clinical trials and save costs.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.kolabtree.com\/blog\/fr\/15-ways-to-reduce-sample-size-in-clinical-trials-infographic\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"[INFOGRAPHIC] 15 Ways to Reduce Sample Size In Clinical Trials\" \/>\n<meta property=\"og:description\" content=\"In this infographic we examine 15 ways and oppportunities for researchers to reduce sample size in clinical trials and save costs.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.kolabtree.com\/blog\/fr\/15-ways-to-reduce-sample-size-in-clinical-trials-infographic\/\" \/>\n<meta property=\"og:site_name\" content=\"The Kolabtree Blog\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/kolabtree\" \/>\n<meta property=\"article:published_time\" content=\"2018-11-21T12:19:49+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2018-11-22T12:09:46+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.kolabtree.com\/blog\/wp-content\/uploads\/2018\/11\/computer-1149148_1280-1.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1280\" \/>\n\t<meta property=\"og:image:height\" content=\"720\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Laura Tobin\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@kolabtree\" \/>\n<meta name=\"twitter:site\" content=\"@kolabtree\" \/>\n<meta name=\"twitter:label1\" content=\"\u00c9crit par\" \/>\n\t<meta name=\"twitter:data1\" content=\"Laura Tobin\" \/>\n\t<meta name=\"twitter:label2\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"[INFOGRAPHIC] 15 Ways to Reduce Sample Size In Clinical Trials - 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