{"id":4989,"date":"2018-11-21T12:19:49","date_gmt":"2018-11-21T12:19:49","guid":{"rendered":"https:\/\/blog.kolabtree.com\/?p=4989"},"modified":"2018-11-22T12:09:46","modified_gmt":"2018-11-22T12:09:46","slug":"15-ways-to-reduce-sample-size-in-clinical-trials-infographic","status":"publish","type":"post","link":"https:\/\/www.kolabtree.com\/blog\/es\/15-maneras-de-reducir-el-tamano-de-la-muestra-en-los-ensayos-clinicos-infografia\/","title":{"rendered":"INFOGR\u00c1FICO] 15 formas de reducir el tama\u00f1o de la muestra en los ensayos cl\u00ednicos"},"content":{"rendered":"

Los costes de los ensayos cl\u00ednicos se han disparado en la \u00faltima d\u00e9cada, y seg\u00fan informes recientes, entre 2008 y 2013 el coste medio por paciente aument\u00f3 en $23.600. Un factor importante que contribuye al coste de un ensayo cl\u00ednico<\/a> es la contrataci\u00f3n de personal y los costes de personal asociados.\u00a0<\/span>Por lo tanto, examinar todas las oportunidades para reducir el tama\u00f1o de la muestra de un estudio es un paso importante y necesario en el desarrollo de f\u00e1rmacos.<\/span>
\n<\/span><\/p>\n

La reducci\u00f3n del tama\u00f1o de la muestra sin perder potencia puede lograrse mediante uno de estos tres principios.<\/span><\/p>\n

En esta infograf\u00eda, examinamos estos aspectos y presentamos 15 formas en que los investigadores pueden reducir el tama\u00f1o de la muestra en los ensayos cl\u00ednicos.<\/span><\/p>\n

\"\"<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
15 formas de reducir el tama\u00f1o de la muestra en los ensayos cl\u00ednicos<\/b><\/td>\n<\/tr>\n
#<\/b><\/td>\nM\u00e9todo<\/b><\/td>\nPosible\u00a0<\/b>Reducci\u00f3n<\/b><\/td>\n<\/tr>\n
1<\/span><\/td>\nAjuste de las variables independientes en el an\u00e1lisis final<\/span><\/td>\n0 – 10%<\/span><\/td>\n<\/tr>\n
2<\/span><\/td>\nEstratificar a los pacientes<\/span><\/td>\n0 - 20%<\/span><\/td>\n<\/tr>\n
3<\/span><\/td>\nEnriquecer a los pacientes<\/span><\/td>\n0 - 20%<\/span><\/td>\n<\/tr>\n
4<\/span><\/td>\nUtilizar la respuesta sostenida<\/span><\/td>\n0 - 25%<\/span><\/td>\n<\/tr>\n
5<\/span><\/td>\nUtilizar comparaciones por pares<\/span><\/td>\n0 - 30%<\/span><\/td>\n<\/tr>\n
6<\/span><\/td>\nAn\u00e1lisis de la frecuencia de uso<\/span><\/td>\n0 - 40%<\/span><\/td>\n<\/tr>\n
7<\/span><\/td>\nUtilizar una t\u00e9cnica estad\u00edstica que se ajuste a la curva de respuesta prevista<\/span><\/td>\n0 - 50%<\/span><\/td>\n<\/tr>\n
8<\/span><\/td>\nUtilizar puntos finales sustitutos<\/span><\/td>\n0 - 70%<\/span><\/td>\n<\/tr>\n
9<\/span><\/td>\nAumentar la tasa de eventos<\/span><\/td>\n0 – 90%<\/span><\/td>\n<\/tr>\n
10<\/span><\/td>\nRealice un ensayo cl\u00ednico ajustado<\/span><\/td>\n5 – 20%<\/span><\/td>\n<\/tr>\n
11<\/span><\/td>\nUtilizar el corte \u00f3ptimo para el punto final binario<\/span><\/td>\n10 - 30%<\/span><\/td>\n<\/tr>\n
12<\/span><\/td>\nUtilizar una variable continua<\/span><\/td>\n10 - 40%<\/span><\/td>\n<\/tr>\n
13<\/span><\/td>\nUtilizar el dise\u00f1o adaptativo<\/span><\/td>\n10 - 50%<\/span><\/td>\n<\/tr>\n
14<\/span><\/td>\nUtilizar estudios cruzados<\/span><\/td>\n50 - 70%<\/span><\/td>\n<\/tr>\n
15<\/span><\/td>\nUtilizar dise\u00f1os factoriales<\/span><\/td>\n50 - 75%<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

Echa un vistazo a la gu\u00eda ampliada en el <\/span>nQuery Tama\u00f1o de la muestra Sitio web del software<\/span><\/a>.<\/span><\/p>\n

\u00bfNecesita ayuda para dise\u00f1ar un ensayo cl\u00ednico? Contratar a expertos cualificados<\/a> en Kolabtree que pueden ayudarle con los m\u00e9todos de recogida de datos, el an\u00e1lisis estad\u00edstico y la validaci\u00f3n, y la optimizaci\u00f3n del dise\u00f1o del estudio. Es gratis publicar su proyecto y obtener presupuestos.
\n<\/b><\/p>\n

 <\/p>","protected":false},"excerpt":{"rendered":"

Clinical trial costs have surged over the past decade, with recent reports stating that from 2008 to 2013, the average cost per patient increased by $23,600. A major contributor to the cost of a clinical trial is subject recruitment and the associated staff costs.\u00a0So, examining every opportunity to reduce the sample size for a study<\/p>\n

Leer m\u00e1s<\/a><\/div>","protected":false},"author":75,"featured_media":5048,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[443,435],"tags":[467,464,459,454,463,458,455,462],"acf":[],"yoast_head":"\n[INFOGRAPHIC] 15 Ways to Reduce Sample Size In Clinical Trials - The Kolabtree Blog<\/title>\n<meta name=\"description\" content=\"In this infographic we examine 15 ways and oppportunities for researchers to reduce sample size in clinical trials and save costs.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.kolabtree.com\/blog\/es\/15-ways-to-reduce-sample-size-in-clinical-trials-infographic\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"[INFOGRAPHIC] 15 Ways to Reduce Sample Size In Clinical Trials\" \/>\n<meta property=\"og:description\" content=\"In this infographic we examine 15 ways and oppportunities for researchers to reduce sample size in clinical trials and save costs.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.kolabtree.com\/blog\/es\/15-ways-to-reduce-sample-size-in-clinical-trials-infographic\/\" \/>\n<meta property=\"og:site_name\" content=\"The Kolabtree Blog\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/kolabtree\" \/>\n<meta property=\"article:published_time\" content=\"2018-11-21T12:19:49+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2018-11-22T12:09:46+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.kolabtree.com\/blog\/wp-content\/uploads\/2018\/11\/computer-1149148_1280-1.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1280\" \/>\n\t<meta property=\"og:image:height\" content=\"720\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Laura Tobin\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@kolabtree\" \/>\n<meta name=\"twitter:site\" content=\"@kolabtree\" \/>\n<meta name=\"twitter:label1\" content=\"Escrito por\" \/>\n\t<meta name=\"twitter:data1\" content=\"Laura Tobin\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tiempo de lectura\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minuto\" \/>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"[INFOGRAPHIC] 15 Ways to Reduce Sample Size In Clinical Trials - 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